SGCG

Name	sarcoglycan gamma
Structure	No pdb structure
Interactors	20 interactors: APP CCT6A CLDN5 DNAJB6 DYSF ENO1 ENO3 FLNC HSPA1B MYBPC1 MYBPC2 MYL11 PSAP PYGM SGCB SGCD SPACA1 SSPN SUCLG2 TTN
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Cytoskeleton Plasma Membrane Dystroglycan Complex Sarcoglycan Complex Membrane Sarcolemma
	Molecular Function	Protein Binding
	Biological Process	Muscle Organ Development Gene Expression Cardiac Muscle Tissue Development Heart Contraction
Pathways	Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)
Diseases	Limb-girdle muscular dystrophy (LGMD) Sarcoglycanopathies, including: Limb-girdle muscular dystrophy (LGMD) 2C; Limb-girdle muscular dystrophy (LGMD) 2D; Limb-girdle muscular dystrophy (LGMD) 2E; Limb-girdle muscular dystrophy (LGMD) 2F
GWAS	Alanine aminotransferase levels ( 31219225 ) Aspartate aminotransferase levels ( 33547301 ) Asthma ( 27611488 ) Atrial fibrillation ( 30061737 ) Bipolar disorder ( 21738484 ) Central corneal thickness ( 29760442 ) Corneal structure ( 23291589 ) Number of alcoholic drinks required to feel an effect (first five times drinking) ( 31270906 ) Recurrent major depressive disorder x sex interaction ( 34099189 ) Type 2 diabetes ( 23300278 )
Entrez ID	6445
HPRD ID	07039
Ensembl ID	ENSG00000102683
Uniprot IDs	Q13326
PDB IDs	Not available
GO Terms Enriched among Interactors ?	M Band Sarcolemma Sarcomere Organization Structural Constituent Of Muscle Actin Filament-based Process Dystrophin-associated Glycoprotein Complex Phosphopyruvate Hydratase Complex Phosphopyruvate Hydratase Activity Muscle Cell Development Actomyosin Structure Organization Cardiac Muscle Cell Development Dystroglycan Complex Actin-mediated Cell Contraction Cardiac Cell Development Sarcoglycan Complex Protein Folding Chaperone Actin Cytoskeleton Organization Actin Filament-based Movement Negative Regulation Of Inclusion Body Assembly Striated Muscle Cell Development Muscle Contraction Actin-myosin Filament Sliding Muscle System Process Extracellular Exosome Canonical Glycolysis Unfolded Protein Binding Glycolytic Process Through Glucose-6-phosphate Glycolytic Process Through Fructose-6-phosphate Carbohydrate Catabolic Process Regulation Of Inclusion Body Assembly Myosin Filament Cell Adhesion Cell Development Nucleoside Phosphate Catabolic Process Glucose Catabolic Process Z Disc Nucleobase-containing Compound Catabolic Process ATP-dependent Protein Folding Chaperone Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of ATP Metabolic Process Positive Regulation Of Toll Signaling Pathway System Process ATP Metabolic Process Organophosphate Catabolic Process Ganglioside GM3 Binding Ganglioside GP1c Binding Positive Regulation Of Beta-galactosidase Activity