MRTFA

Description		myocardin related transcription factor A
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Transcription Coactivator Activity Actin Binding Actin Monomer Binding Protein Binding Leucine Zipper Domain Binding
	Biological Process	Actin Cytoskeleton Organization Wound Healing, Spreading Of Cells Positive Regulation Of Transcription By RNA Polymerase II Smooth Muscle Cell Differentiation Positive Regulation Of MiRNA Transcription
Pathways		SUMOylation of transcription cofactors RHO GTPases Activate Formins
Drugs		Latrunculin B
Diseases
GWAS		Appendicular lean mass ( 33097823)
Interacting Genes		12 interacting genes: KDM3A MAP1LC3A MAP1LC3B MRTFB MVP MYOCD NCOA3 SMARCA4 SRF SUMO1 TRIM54 UBE2I
Entrez ID		57591
HPRD ID		10445
Ensembl ID		ENSG00000196588
Uniprot IDs		A0A494BZX7 A0A499FIJ6 A4FUJ8 B0QY83 Q969V6 W0Z7M9
PDB IDs		2KVU 2KW9
Enriched GO Terms of Interacting Partners?		Positive Regulation Of MiRNA Metabolic Process Positive Regulation Of MiRNA Transcription Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Smooth Muscle Cell Differentiation Cardiac Vascular Smooth Muscle Cell Differentiation Small Protein Activating Enzyme Binding Regulation Of Stem Cell Population Maintenance Vascular Associated Smooth Muscle Cell Differentiation Negative Regulation Of Amyloid-beta Clearance Cardiac Muscle Cell Myoblast Differentiation Nuclear Pore Cellular Response To Nitrogen Starvation Transcription Coactivator Activity Cardioblast Differentiation Phosphatidylethanolamine Binding Regulation Of Transcription By RNA Polymerase II Muscle Cell Differentiation Regulation Of Amyloid-beta Clearance Transcription Factor Binding Positive Regulation Of Transcription By RNA Polymerase II Protein-containing Complex Disassembly Nuclear Androgen Receptor Binding Presynaptic Cytosol Postsynaptic Cytosol Positive Regulation Of Smooth Muscle Contraction Regulation Of Muscle Contraction Myoblast Differentiation Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Transcription Coregulator Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Multicellular Organismal Process Positive Regulation Of DNA-templated Transcription Regulation Of Smooth Muscle Cell Differentiation Glutamatergic Synapse Organelle Membrane Cardiocyte Differentiation Positive Regulation Of Stem Cell Population Maintenance Chromatin Positive Regulation Of Muscle Contraction Autophagosome Maturation Regulation Of RNA Metabolic Process Transcription Initiation-coupled Chromatin Remodeling Regulation Of Muscle System Process Protein Sumoylation Positive Regulation Of Gene Expression, Epigenetic Serum Response Element Binding Cellular Response To Nutrient Levels SUMO Conjugating Enzyme Activity
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