GPR158

Description		G protein-coupled receptor 158
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GO Annotations	Cellular Component	Nucleus Plasma Membrane Membrane Presynaptic Membrane Cell Projection Synapse Postsynaptic Membrane Postsynaptic Density Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Enzyme Activator Activity G Protein-coupled Glycine Receptor Activity
	Biological Process	Positive Regulation Of Neurotransmitter Secretion Signal Transduction G Protein-coupled Receptor Signaling Pathway Brain Development Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Synapse Organization Cognition Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS		Carboplatin disposition in epthelial ovarian cancer ( 29367611) Central corneal thickness ( 32528159) Cerebellum white matter volume ( 31530798) Diverticular disease ( 30177863 30661054) Energy expenditure (24h) ( 28476931) Hepatitis C (spontaneous viral clearance) ( 30593799) Immune response to smallpox vaccine (IL-6) ( 22542470) Intelligence (MTAG) ( 29326435) Intraocular pressure ( 29235454 29617998) QRS duration in Tripanosoma cruzi seropositivity ( 24324551)
Novel Interacting Genes		6 novel interacting genes: ACBD5 APBB1IP ENKUR MASTL MKX PRTFDC1
Interacting Genes
Entrez ID		57512
HPRD ID		13601
Ensembl ID		ENSG00000151025
Uniprot IDs		Q5T848
PDB IDs		7EWL 7EWP 7EWR 7SHE 7SHF
Enriched GO Terms of Interacting Partners?		Hypoxanthine Phosphoribosyltransferase Activity Guanine Salvage Female Meiosis II T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Purine Ribonucleoside Salvage Guanine Metabolic Process GMP Catabolic Process Purine Nucleobase Biosynthetic Process Microtubule Cytoskeleton Establishment Of Left/right Asymmetry Axonemal B Tubule Inner Sheath 9+0 Motile Cilium Purine Nucleoside Monophosphate Catabolic Process Nucleoside Salvage Fatty-acyl-CoA Binding T Cell Receptor Complex Purine Nucleobase Metabolic Process Female Meiotic Nuclear Division Pexophagy
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