GPR158

Name	G protein-coupled receptor 158
Structure
Novel Interactors	6 novel interactors: ACBD5 APBB1IP ENKUR MASTL MKX PRTFDC1
Interactors	None recorded
GO Annotations	Cellular Component	Nucleus Plasma Membrane Membrane Presynaptic Membrane Cell Projection Synapse Postsynaptic Membrane Postsynaptic Density Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Enzyme Activator Activity G Protein-coupled Glycine Receptor Activity
	Biological Process	Positive Regulation Of Neurotransmitter Secretion Signal Transduction G Protein-coupled Receptor Signaling Pathway Brain Development Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Synapse Organization Cognition Protein Localization To Plasma Membrane
GWAS	Carboplatin disposition in epthelial ovarian cancer ( 29367611 ) Central corneal thickness ( 32528159 ) Cerebellum white matter volume ( 31530798 ) Diverticular disease ( 30177863 30661054 ) Energy expenditure (24h) ( 28476931 ) Hepatitis C (spontaneous viral clearance) ( 30593799 ) Immune response to smallpox vaccine (IL-6) ( 22542470 ) Intelligence (MTAG) ( 29326435 ) Intraocular pressure ( 29235454 29617998 ) QRS duration in Tripanosoma cruzi seropositivity ( 24324551 )
Entrez ID	57512
HPRD ID	13601
Ensembl ID	ENSG00000151025
Uniprot IDs	Q5T848
PDB IDs	7EWL 7EWP 7EWR 7SHE 7SHF
GO Terms Enriched among Interactors ?	Hypoxanthine Phosphoribosyltransferase Activity Guanine Salvage Female Meiosis II T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Purine Ribonucleoside Salvage Guanine Metabolic Process GMP Catabolic Process Purine Nucleobase Biosynthetic Process Microtubule Cytoskeleton Establishment Of Left/right Asymmetry Axonemal B Tubule Inner Sheath 9+0 Motile Cilium Purine Nucleoside Monophosphate Catabolic Process Nucleoside Salvage Fatty-acyl-CoA Binding T Cell Receptor Complex Purine Nucleobase Metabolic Process Female Meiotic Nuclear Division Pexophagy