GPR158 and MKX

		GPR158	MKX
Description		G protein-coupled receptor 158	mohawk homeobox
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Membrane Presynaptic Membrane Cell Projection Synapse Postsynaptic Membrane Postsynaptic Density Membrane	Chromatin Nucleus
	Molecular Function	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Enzyme Activator Activity G Protein-coupled Glycine Receptor Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding
	Biological Process	Positive Regulation Of Neurotransmitter Secretion Signal Transduction G Protein-coupled Receptor Signaling Pathway Brain Development Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Synapse Organization Cognition Protein Localization To Plasma Membrane	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Muscle Organ Development Cell Development
Pathways
Drugs
Diseases
GWAS		Carboplatin disposition in epthelial ovarian cancer ( 29367611) Central corneal thickness ( 32528159) Cerebellum white matter volume ( 31530798) Diverticular disease ( 30177863 30661054) Energy expenditure (24h) ( 28476931) Hepatitis C (spontaneous viral clearance) ( 30593799) Immune response to smallpox vaccine (IL-6) ( 22542470) Intelligence (MTAG) ( 29326435) Intraocular pressure ( 29235454 29617998) QRS duration in Tripanosoma cruzi seropositivity ( 24324551)	Childhood ear infection ( 27182965 28928442) Diisocyanate-induced asthma ( 25918132) Heel bone mineral density ( 30598549) Height ( 28552196 31562340) Hip circumference adjusted for BMI ( 34021172) Immune response to smallpox vaccine (IL-6) ( 22542470) Retinal detachment or retinal break ( 31816047) Trunk fat mass ( 28552196)
Interacting Genes
Entrez ID		57512	283078
HPRD ID		13601	12577
Ensembl ID		ENSG00000151025	ENSG00000150051
Uniprot IDs		Q5T848	Q8IYA7
PDB IDs		7EWL 7EWP 7EWR 7SHE 7SHF
Enriched GO Terms of Interacting Partners?		Hypoxanthine Phosphoribosyltransferase Activity Guanine Salvage Female Meiosis II T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Purine Ribonucleoside Salvage Guanine Metabolic Process GMP Catabolic Process Purine Nucleobase Biosynthetic Process Microtubule Cytoskeleton Establishment Of Left/right Asymmetry Axonemal B Tubule Inner Sheath 9+0 Motile Cilium Purine Nucleoside Monophosphate Catabolic Process Nucleoside Salvage Fatty-acyl-CoA Binding T Cell Receptor Complex Purine Nucleobase Metabolic Process Female Meiotic Nuclear Division Pexophagy	G Protein-coupled Glycine Receptor Activity Cognition Nervous System Process Positive Regulation Of Neurotransmitter Secretion GABA Receptor Binding
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