EPS8L1

Gene Name		EPS8-like 1
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Ruffle Membrane Protein Complex Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding Rac Guanyl-nucleotide Exchange Factor Activity T Cell Receptor Binding
	Biological Process	Rho Protein Signal Transduction Positive Regulation Of Rho GTPase Activity Positive Regulation Of Rac GTPase Activity Regulation Of Rho Protein Signal Transduction Positive Regulation Of Ruffle Assembly
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: ABI1 ACTN2 SOS1 TERF2IP
Entrez ID		54869
HPRD ID		13276
Ensembl ID		ENSG00000131037
Uniprot IDs		B4DKV7 Q8TE68
PDB IDs		2K2M 2ROL
Enriched GO Terms of Interacting Partners?		Negative Regulation Of DNA Recombination At Telomere Platelet Activation Cell Projection Organization Response To Stress Fc Receptor Signaling Pathway Lamellipodium Morphogenesis Protection From Non-homologous End Joining At Telomere Telomere Capping Protein Localization To Chromosome, Telomeric Region Microspike Assembly Movement Of Cell Or Subcellular Component Negative Regulation Of Protein Localization To Cell Surface Immune Response-regulating Cell Surface Receptor Signaling Pathway Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Blood Coagulation Hemostasis Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Double-strand Break Repair Via Homologous Recombination Immune Response-regulating Signaling Pathway Negative Regulation Of Potassium Ion Transmembrane Transport Megakaryocyte Development Positive Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Telomere Maintenance Regulation Of Protein Localization To Cell Surface Regulation Of Body Fluid Levels RNA-dependent DNA Replication Wound Healing Negative Regulation Of Potassium Ion Transport Negative Regulation Of DNA Recombination Positive Regulation Of ERBB Signaling Pathway Megakaryocyte Differentiation Actin Filament-based Process Regulation Of Double-strand Break Repair Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Potassium Ion Transmembrane Transporter Activity Cell Activation Positive Regulation Of Potassium Ion Transport Protein Localization To Chromosome Response To Wounding Telomere Maintenance Via Telomere Lengthening Actin-myosin Filament Sliding Focal Adhesion Assembly Muscle Filament Sliding Regulation Of Signal Transduction Positive Regulation Of Protein Tyrosine Kinase Activity Regulation Of Potassium Ion Transmembrane Transport Innate Immune Response
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