PDP1

Gene Name		pyruvate dehyrogenase phosphatase catalytic subunit 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Matrix
	Molecular Function	Protein Serine/threonine Phosphatase Activity [pyruvate Dehydrogenase (lipoamide)] Phosphatase Activity Metal Ion Binding
	Biological Process	Pyruvate Metabolic Process Regulation Of Acetyl-CoA Biosynthetic Process From Pyruvate Peptidyl-threonine Dephosphorylation Cellular Metabolic Process Small Molecule Metabolic Process
Pathways		Regulation of pyruvate dehydrogenase (PDH) complex Pyruvate metabolism Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: CBFA2T2 PDHA1 PRKCD
Entrez ID		54704
HPRD ID		16185
Ensembl ID		ENSG00000164951
Uniprot IDs		Q6P1N1 Q9P0J1
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cell Projection Organization Positive Regulation Of Phospholipid Scramblase Activity Positive Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Sphingomyelin Catabolic Process Positive Regulation Of Phospholipid Catabolic Process Interleukin-10 Production Negative Regulation Of Filopodium Assembly Acetyl-CoA Biosynthetic Process From Pyruvate Regulation Of Lipid Metabolic Process Interleukin-12 Production Positive Regulation Of Ceramide Biosynthetic Process Regulation Of Ceramide Biosynthetic Process Acetyl-CoA Biosynthetic Process Positive Regulation Of Phospholipid Transport Negative Regulation Of Platelet Aggregation Positive Regulation Of Superoxide Anion Generation Negative Regulation Of Glial Cell Apoptotic Process Regulation Of Cell Projection Organization Regulation Of Cellular Ketone Metabolic Process Regulation Of Superoxide Anion Generation Regulation Of Platelet Aggregation Regulation Of Acetyl-CoA Biosynthetic Process From Pyruvate Negative Regulation Of Platelet Activation Regulation Of Acyl-CoA Biosynthetic Process Positive Regulation Of Protein Dephosphorylation Neutrophil Activation Acetyl-CoA Metabolic Process Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Positive Regulation Of Lipid Catabolic Process Regulation Of Platelet Activation Cellular Senescence Negative Regulation Of Insulin Receptor Signaling Pathway B Cell Proliferation Tricarboxylic Acid Cycle Negative Regulation Of Peptidyl-tyrosine Phosphorylation Citrate Metabolic Process Regulation Of Filopodium Assembly Peptidyl-threonine Phosphorylation Positive Regulation Of Dephosphorylation Activation Of Phospholipase C Activity Negative Regulation Of Blood Coagulation Tricarboxylic Acid Metabolic Process Negative Regulation Of Protein Binding Positive Regulation Of Phospholipase C Activity Positive Regulation Of Transporter Activity Regulation Of Lipid Catabolic Process Negative Regulation Of Coagulation Positive Regulation Of Lipid Transport Positive Regulation Of Lipid Biosynthetic Process Aerobic Respiration
Tagcloud ?		acat1 acetyltransferase aerobic attached attenuate attenuation catabolize concert covalently dehydrogenase dihydrolipoyl dissociates glycolysis l2 lipoic pdc pdh pdha1 pdk pyruvate recruit recruits rely sirt3 switch tyr warburg y94f