TRAPPC12

Description		trafficking protein particle complex subunit 12
Image		No pdb structure
GO Annotations	Cellular Component	Kinetochore Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol TRAPP Complex Perinuclear Region Of Cytoplasm TRAPPIII Protein Complex
	Molecular Function	Protein Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Vesicle-mediated Transport COPII Vesicle Coating Metaphase Chromosome Alignment Regulation Of Kinetochore Assembly Vesicle Tethering Positive Regulation Of Protein Localization To Kinetochore
Pathways		RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Neuritic plaques or neurofibrillary tangles or cerebral amyloid angiopathy (pleiotropy) ( 29458411) Serum immune biomarker levels ( 32066700)
Interacting Genes		13 interacting genes: BMAL1 FBXO7 HNRNPA2B1 LIN7B MTDH RSKR TFCP2 TRAPPC10 TRAPPC3L TRAPPC4 TRAPPC6A TRAPPC6B TRAPPC9
Entrez ID		51112
HPRD ID		15580
Ensembl ID		ENSG00000171853
Uniprot IDs		A0A0J9YXQ9 Q8WVT3
PDB IDs
Enriched GO Terms of Interacting Partners?		TRAPP Complex Vesicle Tethering Vesicle Coating TRAPPII Protein Complex Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Vesicle Transport Vesicle Organization Establishment Of Localization In Cell Vesicle-mediated Transport Intracellular Transport TRAPPIII Protein Complex Cellular Localization COPII Vesicle Coating Golgi Apparatus Intra-Golgi Vesicle-mediated Transport Trans-Golgi Network Endoplasmic Reticulum Cis-Golgi Network Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Oxidative Stress-induced Premature Senescence MiRNA Transport Lewy Body Core Postsynaptic Density Membrane
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