PCSK6

Gene Name		proprotein convertase subtilisin/kexin type 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Golgi Lumen Cell Surface Membrane Extracellular Matrix
	Molecular Function	Endopeptidase Activity Serine-type Endopeptidase Activity Heparin Binding Nerve Growth Factor Binding
	Biological Process	Proteolysis Zygotic Determination Of Anterior/posterior Axis, Embryo Determination Of Left/right Symmetry Glycoprotein Metabolic Process Protein Processing Peptide Hormone Processing Regulation Of BMP Signaling Pathway Nerve Growth Factor Processing Nerve Growth Factor Production Secretion By Cell Neurotrophin TRK Receptor Signaling Pathway
Pathways		Signalling by NGF NGF processing Signaling by NODAL
Drugs
Diseases
GWAS		Handedness in dyslexia ( 21051773)
Protein-protein Interactions		4 interactors: CACNA1A FLG PMCH RCN3
Entrez ID		5046
HPRD ID		01329
Ensembl ID		ENSG00000140479
Uniprot IDs		P29122
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell-cell Signaling Cerebellar Molecular Layer Development Vestibular Nucleus Development Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Gamma-aminobutyric Acid Secretion Regulation Of Lateral Mesodermal Cell Fate Specification Fibroblast Growth Factor Receptor Signaling Pathway Involved In Orbitofrontal Cortex Development Ventricular Zone Neuroblast Division Regulation Of Acetylcholine Secretion, Neurotransmission Orbitofrontal Cortex Development Rhythmic Synaptic Transmission Regulation Of Neuron Projection Development Forebrain Ventricular Zone Progenitor Cell Division Positive Regulation Of MAPKKK Cascade By Fibroblast Growth Factor Receptor Signaling Pathway Calcium Ion-dependent Exocytosis Of Neurotransmitter Cellular Chloride Ion Homeostasis Gamma-aminobutyric Acid Transport Chloride Ion Homeostasis Outer Ear Morphogenesis Regulation Of Branching Involved In Salivary Gland Morphogenesis By Mesenchymal-epithelial Signaling Regulation Of Cell Projection Organization Negative Regulation Of Hormone Biosynthetic Process Pons Development Regulation Of Neuron Differentiation Cell Morphogenesis Involved In Neuron Differentiation Synaptic Transmission Cerebellar Purkinje Cell Differentiation Mesenchymal-epithelial Cell Signaling Behavior Forebrain Neuroblast Division Regulation Of Branching Involved In Salivary Gland Morphogenesis Neuron Projection Morphogenesis Establishment Of Skin Barrier Cerebellar Purkinje Cell Layer Morphogenesis Auditory Receptor Cell Development Lung-associated Mesenchyme Development Cell Surface Receptor Signaling Pathway Regulation Of Cell Fate Specification Regulation Of Water Loss Via Skin Regulation Of Neurogenesis Reflex Cell Morphogenesis Involved In Differentiation Behavioral Response To Pain Neuromuscular Synaptic Transmission Cell Differentiation Brain Development Regulation Of Hormone Biosynthetic Process Paraxial Mesoderm Development Middle Ear Morphogenesis
Tagcloud ?		absent astrocytic cadherin candidate cdh11 convertase endocytosis functionally glioblastoma glioblastomas glioma gliomas immunoreactivity infiltrating infiltration infiltrative invasion kexin microdissected ontology proprotein rich sh3 sh3gl3 subtilisin tumour validate validated zone