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NUCB1
Description
nucleobindin 1
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cytoplasm
Endoplasmic Reticulum Lumen
Endoplasmic Reticulum-Golgi Intermediate Compartment
Golgi Apparatus
Endomembrane System
Membrane
Extracellular Exosome
Molecular Function
G-protein Alpha-subunit Binding
DNA Binding
Guanyl-nucleotide Exchange Factor Activity
Calcium Ion Binding
Protein Binding
Metal Ion Binding
Biological Process
Small GTPase-mediated Signal Transduction
Pathways
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation
Drugs
Calcium citrate
Calcium Phosphate
Calcium phosphate dihydrate
Diseases
GWAS
Novel Interacting Genes
1 novel interacting genes:
PLOD2
Interacting Genes
18 interacting genes:
DYRK1A
GNAI1
GNAI2
GNAI3
GNAO1
GNAS
GNAZ
HIVEP1
HOXA1
MYC
NDN
PTGS1
PTGS2
RBL1
REL
SET
SIRPA
XPO1
Entrez ID
4924
HPRD ID
03205
Ensembl ID
ENSG00000104805
Uniprot IDs
A8K7Q1
Q02818
PDB IDs
1SNL
Enriched GO Terms of Interacting Partners
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Guanyl Nucleotide Binding
G-protein Beta/gamma-subunit Complex Binding
Heterotrimeric G-protein Complex
G Protein-coupled Serotonin Receptor Binding
Adenylate Cyclase Regulator Activity
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
GTPase Activity
G Protein-coupled Receptor Binding
Mu-type Opioid Receptor Binding
G Protein-coupled Serotonin Receptor Signaling Pathway
GTP Binding
Cyclooxygenase Pathway
Prostaglandin-endoperoxide Synthase Activity
Adenylate Cyclase Inhibitor Activity
Corticotropin-releasing Hormone Receptor 1 Binding
Negative Regulation Of Insulin Secretion
Negative Regulation Of Peptide Secretion
Negative Regulation Of Secretion By Cell
Regulation Of Insulin Secretion
Negative Regulation Of Secretion
Positive Regulation Of Metabolic Process
Adenylate Cyclase-inhibiting Serotonin Receptor Signaling Pathway
Negative Regulation Of Adenylate Cyclase Activity
Negative Regulation Of Hormone Secretion
Regulation Of Peptide Hormone Secretion
G Protein Activity
Negative Regulation Of Protein Secretion
Oxidoreductase Activity, Acting On Single Donors With Incorporation Of Molecular Oxygen, Incorporation Of Two Atoms Of Oxygen
Negative Regulation Of Transport
Dioxygenase Activity
Regulation Of Protein Transport
Cell Body
Negative Regulation Of Cell Communication
Regulation Of Metabolic Process
Negative Regulation Of Signaling
Negative Regulation Of Interferon-beta Production
Prostaglandin Biosynthetic Process
G Protein-coupled Receptor Signaling Pathway
Regulation Of Hormone Secretion
Regulation Of Protein Secretion
Prostanoid Biosynthetic Process
Regulation Of Establishment Of Protein Localization
Negative Regulation Of Macromolecule Biosynthetic Process
G Protein-coupled Dopamine Receptor Signaling Pathway
Protein-DNA Complex Disassembly
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Protein Transport
Regulation Of Secretion By Cell
Response To Prostaglandin E
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