MDH1

Gene Name		malate dehydrogenase 1, NAD (soluble)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytoplasm Mitochondrion Centrosome Cytosol Extracellular Vesicular Exosome
	Molecular Function	Malic Enzyme Activity L-malate Dehydrogenase Activity Diiodophenylpyruvate Reductase Activity NAD Binding
	Biological Process	Carbohydrate Metabolic Process Glucose Metabolic Process Gluconeogenesis Tricarboxylic Acid Cycle Oxaloacetate Metabolic Process Malate Metabolic Process NADH Metabolic Process Pathogenesis Cellular Carbohydrate Metabolic Process Small Molecule Metabolic Process
Pathways		Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates
Drugs		NADH Nicotinamide-Adenine-Dinucleotide 2\'-Monophosphoadenosine 5\'-Diphosphoribose
Diseases
GWAS
Protein-protein Interactions		7 interactors: EGFR FUS GPD1 MPP3 TERF1 TERF2IP TP53
Entrez ID		4190
HPRD ID		01100
Ensembl ID		ENSG00000014641
Uniprot IDs		P40925
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of DNA Metabolic Process Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of DNA Replication Regulation Of Telomere Maintenance RNA-dependent DNA Replication Regulation Of Chromosome Organization Negative Regulation Of Mitotic Cell Cycle Telomere Maintenance Via Telomere Lengthening Positive Regulation Of Cell Cycle Negative Regulation Of DNA Replication Cellular Response To Drug Regulation Of DNA Repair Regulation Of Mitotic Cell Cycle Cell Aging Negative Regulation Of Cell Cycle Telomere Maintenance Response To Osmotic Stress Positive Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of Chromosome Organization Alkanesulfonate Metabolic Process Glycerophosphate Shuttle Negative Regulation Of DNA Recombination At Telomere Nucleobase-containing Compound Metabolic Process Response To Drug Regulation Of Fibroblast Proliferation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Protein Catabolic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Macromitophagy Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Oligodendrocyte Apoptotic Process Astrocyte Activation Regulation Of Response To DNA Damage Stimulus Response To UV Mitotic Cell Cycle Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Reactive Oxygen Species Metabolic Process Mitochondrial Transport Negative Regulation Of Helicase Activity Telomeric Loop Formation Age-dependent Telomere Shortening Nitrogen Compound Metabolic Process Mitotic Cell Cycle Checkpoint Mitotic Cell Cycle Circadian Rhythm Positive Regulation Of Protein Complex Assembly Telomere Maintenance Via Telomere Shortening
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