KLK1

Gene Name		kallikrein 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Extracellular Vesicular Exosome
	Molecular Function	Serine-type Endopeptidase Activity
	Biological Process	Proteolysis
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Drugs		Aprotinin
Diseases
GWAS
Protein-protein Interactions		3 interactors: KNG1 SERPINA4 SERPINA5
Entrez ID		3816
HPRD ID		01003
Ensembl ID		ENSG00000167748
Uniprot IDs		F8WAM8 P06870
PDB IDs		1SPJ
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Regulation Of Endopeptidase Activity Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Regulation Of Peptidase Activity Regulation Of Proteolysis Negative Regulation Of Catalytic Activity Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Blood Coagulation Hemostasis Regulation Of Catalytic Activity Positive Regulation Of Renal Sodium Excretion Regulation Of Body Fluid Levels Wound Healing Positive Regulation Of Urine Volume Blood Coagulation, Intrinsic Pathway Fusion Of Sperm To Egg Plasma Membrane Plasma Membrane Fusion Response To Wounding Regulation Of Renal Sodium Excretion Regulation Of Excretion Vasodilation Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Smooth Muscle Contraction Negative Regulation Of Wound Healing Platelet Degranulation Regulation Of Blood Vessel Size Regulation Of Tube Size Renal System Process Regulation Of Blood Coagulation Membrane Fusion Regulation Of Wound Healing Single Fertilization Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Ion Homeostasis Protein Activation Cascade Fertilization Cytosolic Calcium Ion Homeostasis Platelet Activation
Tagcloud ?		b2 bradykinin cancers diverse du145 emanating endometrial enzymic exhibit expressed implicated kallikrein kinin lncap member members organs particular prostate proteases range reproductive serine structurally tissue tumorigenesis uterus varying