KISS1

Description		KiSS-1 metastasis suppressor
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Protein Binding Kisspeptin Receptor Binding
	Biological Process	Cytoskeleton Organization G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Luteinizing Hormone Secretion
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events
Drugs
Diseases
GWAS		Psychosis proneness (hypomanic personality scale and perceptual aberration scale) ( 28525603) Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale) ( 28525603) Psychosis proneness (hypomanic personality scale and revised social anhedonia scale) ( 28525603) Psychosis proneness (hypomanic personality scale) ( 28525603) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309)
Interacting Genes		9 interacting genes: APP CREBBP KISS1R MMP14 MMP16 MMP2 MMP24 MMP9 UBQLN2
Entrez ID		3814
HPRD ID		04475
Ensembl ID		ENSG00000170498
Uniprot IDs		Q15726
PDB IDs		8XGS 8ZJD
Enriched GO Terms of Interacting Partners?		Collagen Catabolic Process Collagen Metabolic Process Extracellular Matrix Organization Extracellular Structure Organization Metalloendopeptidase Activity Metallopeptidase Activity Endodermal Cell Differentiation Extracellular Matrix Peptidase Activity Extracellular Matrix Disassembly Response To Amyloid-beta Protein Metabolic Process Proteolysis Cellular Response To UV-A Cellular Response To UV Endopeptidase Activity Response To Light Stimulus Golgi Lumen Response To UV-A Cellular Response To Light Stimulus Chondrocyte Proliferation Skeletal System Morphogenesis Extracellular Space Craniofacial Suture Morphogenesis Ossification Response To Radiation Serine-type Endopeptidase Activity Response To UV Metalloaminopeptidase Activity Cellular Response To Radiation Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Cellular Response To Stress Skeletal System Development Embryonic Cranial Skeleton Morphogenesis Endochondral Ossification Positive Regulation Of Cell Migration Response To Mechanical Stimulus Zinc Ion Binding Catabolic Process Positive Regulation Of Proteolysis Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Positive Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Embryo Implantation Macromolecule Metabolic Process Ovarian Follicle Development Ephrin Receptor Signaling Pathway Regulation Of Cell Communication Regulation Of Signaling
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