KCNE1

Gene Name		potassium channel, voltage gated subfamily E regulatory beta subunit 1
Image
Gene Ontology Annotations	Cellular Component	Lysosome Plasma Membrane Voltage-gated Potassium Channel Complex Cell Surface Z Disc
	Molecular Function	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Potassium Channel Regulator Activity Telethonin Binding Voltage-gated Potassium Channel Activity Involved In Cardiac Muscle Cell Action Potential Repolarization Voltage-gated Potassium Channel Activity Involved In Ventricular Cardiac Muscle Cell Action Potential Repolarization
	Biological Process	Protein N-linked Glycosylation Protein O-linked Glycosylation Sensory Perception Of Sound Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Cellular Response To CAMP Potassium Ion Export Potassium Ion Transmembrane Transport Cardiac Muscle Cell Action Potential Involved In Contraction Ventricular Cardiac Muscle Cell Action Potential Membrane Repolarization Membrane Repolarization During Action Potential Membrane Repolarization During Cardiac Muscle Cell Action Potential Regulation Of Heart Rate By Cardiac Conduction Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Potassium Ion Transmembrane Transport Regulation Of Delayed Rectifier Potassium Channel Activity
Pathways
Drugs		Indapamide
Diseases
GWAS		Electrocardiographic traits ( 20062063)
Protein-protein Interactions		6 interactors: ADRB2 KCNH2 KCNQ1 PRKCA TPM3 UBASH3A
Entrez ID		3753
HPRD ID		01442
Ensembl ID		ENSG00000180509
Uniprot IDs		A7LFK2 A7LFK4 A8MWV9 C7S316 P15382 Q6FHJ6
PDB IDs		2K21
Enriched GO Terms of Interacting Partners?		Regulation Of Muscle Contraction Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Potassium Ion Export Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Membrane Repolarization Regulation Of Heart Contraction Positive Regulation Of Potassium Ion Transmembrane Transport Ventricular Cardiac Muscle Cell Action Potential Regulation Of Membrane Repolarization Regulation Of Heart Rate By Cardiac Conduction Muscle Contraction Cardiac Muscle Cell Action Potential Involved In Contraction Activation Of Adenylate Cyclase Activity Positive Regulation Of Potassium Ion Transport Muscle System Process Positive Regulation Of Adenylate Cyclase Activity Cardiac Muscle Cell Action Potential Regulation Of Potassium Ion Transmembrane Transport Blood Circulation Regulation Of Cardiac Muscle Cell Contraction Cardiac Conduction Positive Regulation Of Lyase Activity Cardiac Muscle Contraction Cellular Response To Drug Regulation Of Adenylate Cyclase Activity Regulation Of Potassium Ion Transport Positive Regulation Of CAMP Biosynthetic Process Heart Contraction Regulation Of Cyclase Activity Positive Regulation Of CAMP Metabolic Process Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Positive Regulation Of Ion Transmembrane Transport Striated Muscle Contraction Positive Regulation Of Cyclic Nucleotide Metabolic Process Action Potential Regulation Of Striated Muscle Contraction Regulation Of CAMP Biosynthetic Process Potassium Ion Export Across Plasma Membrane Negative Regulation Of Potassium Ion Export Positive Regulation Of Dense Core Granule Biogenesis Regulation Of CAMP Metabolic Process Synaptic Transmission Regulation Of Ion Transport Regulation Of Cellular Component Movement Regulation Of Heart Rate By Hormone Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin Histone H3-T6 Phosphorylation Vasodilation By Norepinephrine-epinephrine Involved In Regulation Of Systemic Arterial Blood Pressure
Tagcloud ?		blockers channels coimmunoprecipitation contractions debate diversity electrophysiological exhibiting fail hek heteromers heterotetrameric heterotetramers kcne3 kv kv7 microdomains muscles myocytes oocyte photobleaching physiology raft shed smooth tune vasoconstriction vasorelaxants vessels