IL15

Gene Name		interleukin 15
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleoplasm Cytoplasm Endosome Golgi Apparatus Integral Component Of Plasma Membrane Cell Surface Membrane
	Molecular Function	Cytokine Activity Cytokine Receptor Binding Protein Binding
	Biological Process	Natural Killer Cell Differentiation NK T Cell Proliferation Inflammatory Response Immune Response Signal Transduction Cell-cell Signaling Aging Positive Regulation Of Cell Proliferation Skeletal Muscle Atrophy Hyaluronan Metabolic Process Positive Regulation Of Interleukin-17 Production Positive Regulation Of Natural Killer Cell Proliferation Positive Regulation Of Natural Killer Cell Differentiation Positive Regulation Of Tissue Remodeling Positive Regulation Of T Cell Proliferation Positive Regulation Of Tyrosine Phosphorylation Of Stat3 Protein Extrathymic T Cell Selection Regulation Of T Cell Differentiation Cell Maturation Lymph Node Development Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Defense Response To Virus By Host Positive Regulation Of Inflammatory Response Positive Regulation Of Immune Response Cellular Response To Vitamin D
Pathways
Drugs
Diseases
GWAS		Response to treatment for acute lymphoblastic leukemia ( 19176441)
Protein-protein Interactions		7 interactors: APP IL15RA IL2RB IL2RG STAT5B TRAF3 ZNRD1
Entrez ID		3600
HPRD ID		02776
Ensembl ID		ENSG00000164136
Uniprot IDs		P40933 Q6FGX7
PDB IDs		2XQB 2Z3Q 2Z3R 4GS7
Enriched GO Terms of Interacting Partners?		Response To Interleukin-2 Cytokine-mediated Signaling Pathway Cellular Response To Cytokine Stimulus Interleukin-2-mediated Signaling Pathway Response To Cytokine Cell Surface Receptor Signaling Pathway Cellular Response To Organic Substance Response To Interleukin-4 Response To Organic Substance Regulation Of Multicellular Organism Growth Positive Regulation Of Mitotic Cell Cycle Interleukin-7-mediated Signaling Pathway Synaptic Growth At Neuromuscular Junction Signal Transduction Collateral Sprouting In Absence Of Injury Signaling Cell Communication Creatinine Metabolic Process Development Of Secondary Male Sexual Characteristics Positive Regulation Of Innate Immune Response Collateral Sprouting Axon Midline Choice Point Recognition Isoleucine Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Allantoin Metabolic Process Positive Regulation Of Natural Killer Cell Proliferation Immune System Process Taurine Metabolic Process Axon Choice Point Recognition Regulation Of Natural Killer Cell Proliferation Regulation Of Innate Immune Response Prolactin Signaling Pathway Response To Interleukin-15 Steroid Metabolic Process Positive Regulation Of Gamma-delta T Cell Differentiation Cellular Response To Stimulus Negative Regulation Of Erythrocyte Differentiation Valine Metabolic Process Neuron Remodeling Creatine Metabolic Process Positive Regulation Of Cell Cycle Positive Regulation Of Gamma-delta T Cell Activation Succinate Metabolic Process Development Of Secondary Female Sexual Characteristics Regulation Of Developmental Growth Toll Signaling Pathway Positive Regulation Of Natural Killer Cell Differentiation Interleukin-4-mediated Signaling Pathway Regulation Of Gamma-delta T Cell Differentiation Development Of Secondary Sexual Characteristics
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