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GUCY1A2
Gene Name
guanylate cyclase 1, soluble, alpha 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Molecular Function
Guanylate Cyclase Activity
GTP Binding
Heme Binding
Biological Process
CGMP Biosynthetic Process
Signal Transduction
Blood Coagulation
Positive Regulation Of CGMP Biosynthetic Process
Intracellular Signal Transduction
Pathways
Platelet homeostasis
Nitric oxide stimulates guanylate cyclase
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Visceral adipose tissue/subcutaneous adipose tissue ratio (
22589738
)
Protein-protein Interactions
8 interactors:
DLG1
DLG2
DLG3
DLG4
ERBB2IP
GUCY1B3
SNTA1
STUB1
Entrez ID
2977
HPRD ID
03146
Ensembl ID
ENSG00000152402
Uniprot IDs
B7ZLT5
P33402
PDB IDs
Enriched GO Terms of Interacting Partners
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Receptor Localization To Synapse
Protein Localization To Synapse
Establishment Or Maintenance Of Apical/basal Cell Polarity
Receptor Clustering
Nucleotide Phosphorylation
Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Establishment Or Maintenance Of Cell Polarity
Nucleotide Metabolic Process
Nucleobase-containing Small Molecule Metabolic Process
Protein Localization To Membrane
Organophosphate Metabolic Process
Synaptic Transmission
Cellular Protein Localization
Cortical Actin Cytoskeleton Organization
Cortical Cytoskeleton Organization
Regulation Of Sodium Ion Transmembrane Transport
Regulation Of Membrane Potential
Membrane Organization
Cell-cell Signaling
Protein Localization
Negative Regulation Of Phosphatase Activity
Regulation Of Sodium Ion Transport
Negative Regulation Of Dephosphorylation
Axon Guidance
Signaling
Regulation Of Ion Transmembrane Transport
Cell Communication
Regulation Of Vasoconstriction By Circulating Norepinephrine
Small Molecule Metabolic Process
Regulation Of Catalytic Activity
Cellular Localization
Regulation Of Phosphatase Activity
Axonogenesis
Positive Regulation Of Chaperone-mediated Protein Complex Assembly
Basal Protein Localization
Axon Development
Cell Morphogenesis Involved In Neuron Differentiation
Regulation Of Dephosphorylation
Chemotaxis
Regulation Of Ion Transport
Neuron Projection Morphogenesis
Nucleobase-containing Compound Metabolic Process
Phosphate-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Positive Regulation Of Protein Complex Assembly
Cell Morphogenesis Involved In Differentiation
Synapse Organization
Negative Regulation Of Peptidyl-cysteine S-nitrosylation
T Cell Cytokine Production
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