GUCY1A2

Gene Name		guanylate cyclase 1, soluble, alpha 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm
	Molecular Function	Guanylate Cyclase Activity GTP Binding Heme Binding
	Biological Process	CGMP Biosynthetic Process Signal Transduction Blood Coagulation Positive Regulation Of CGMP Biosynthetic Process Intracellular Signal Transduction
Pathways		Platelet homeostasis Nitric oxide stimulates guanylate cyclase
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Protein-protein Interactions		8 interactors: DLG1 DLG2 DLG3 DLG4 ERBB2IP GUCY1B3 SNTA1 STUB1
Entrez ID		2977
HPRD ID		03146
Ensembl ID		ENSG00000152402
Uniprot IDs		B7ZLT5 P33402
PDB IDs
Enriched GO Terms of Interacting Partners?		Receptor Localization To Synapse Protein Localization To Synapse Establishment Or Maintenance Of Apical/basal Cell Polarity Receptor Clustering Nucleotide Phosphorylation Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Establishment Or Maintenance Of Cell Polarity Nucleotide Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Protein Localization To Membrane Organophosphate Metabolic Process Synaptic Transmission Cellular Protein Localization Cortical Actin Cytoskeleton Organization Cortical Cytoskeleton Organization Regulation Of Sodium Ion Transmembrane Transport Regulation Of Membrane Potential Membrane Organization Cell-cell Signaling Protein Localization Negative Regulation Of Phosphatase Activity Regulation Of Sodium Ion Transport Negative Regulation Of Dephosphorylation Axon Guidance Signaling Regulation Of Ion Transmembrane Transport Cell Communication Regulation Of Vasoconstriction By Circulating Norepinephrine Small Molecule Metabolic Process Regulation Of Catalytic Activity Cellular Localization Regulation Of Phosphatase Activity Axonogenesis Positive Regulation Of Chaperone-mediated Protein Complex Assembly Basal Protein Localization Axon Development Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Dephosphorylation Chemotaxis Regulation Of Ion Transport Neuron Projection Morphogenesis Nucleobase-containing Compound Metabolic Process Phosphate-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Protein Complex Assembly Cell Morphogenesis Involved In Differentiation Synapse Organization Negative Regulation Of Peptidyl-cysteine S-nitrosylation T Cell Cytokine Production See more
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