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GRM2
Gene Name
glutamate receptor, metabotropic 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Intracellular
Plasma Membrane
Integral Component Of Plasma Membrane
Cell Junction
Axon
Dendrite
Presynaptic Membrane
Molecular Function
Group II Metabotropic Glutamate Receptor Activity
G-protein Coupled Receptor Activity
Calcium Channel Regulator Activity
Glutamate Receptor Activity
Biological Process
Negative Regulation Of Adenylate Cyclase Activity
Adenylate Cyclase-inhibiting G-protein Coupled Glutamate Receptor Signaling Pathway
Synaptic Transmission
Glutamate Secretion
Regulation Of Synaptic Transmission, Glutamatergic
Pathways
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
GPCR downstream signaling
G alpha (i) signalling events
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
Class C/3 (Metabotropic glutamate/pheromone receptors)
Drugs
Acamprosate
Diseases
GWAS
Protein-protein Interactions
6 interactors:
GNA15
GNAQ
GRASP
NAALADL2
RGS12
UBQLN1
Entrez ID
2912
HPRD ID
04977
Ensembl ID
ENSG00000164082
Uniprot IDs
Q14416
Q86YG3
PDB IDs
Enriched GO Terms of Interacting Partners
?
Phospholipase C-activating Dopamine Receptor Signaling Pathway
Dopamine Receptor Signaling Pathway
Activation Of Phospholipase C Activity
Positive Regulation Of Phospholipase C Activity
Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway
Positive Regulation Of Phospholipase Activity
Regulation Of Phospholipase Activity
Positive Regulation Of Lipase Activity
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Phospholipase C-activating G-protein Coupled Acetylcholine Receptor Signaling Pathway
Platelet Activation
Positive Regulation Of Hydrolase Activity
Cellular Response To Stimulus
Neuron Remodeling
Positive Regulation Of Catalytic Activity
Regulation Of Melanocyte Differentiation
G-protein Coupled Acetylcholine Receptor Signaling Pathway
Blood Coagulation
Hemostasis
Maternal Behavior
Regulation Of Catenin Import Into Nucleus
Regulation Of Developmental Pigmentation
Response To Stimulus
Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway
Regulation Of Body Fluid Levels
Wound Healing
Neuron Maturation
Cell Activation
Forebrain Neuron Development
Response To Wounding
Regulation Of Catalytic Activity
Positive Regulation Of GTPase Activity
Signal Transduction
Regulation Of GTPase Activity
Regulation Of Cellular Response To Oxidative Stress
Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway
Signaling
Forebrain Neuron Differentiation
Glutamate Receptor Signaling Pathway
Termination Of G-protein Coupled Receptor Signaling Pathway
Cell Communication
Developmental Pigmentation
Termination Of Signal Transduction
Tagcloud
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asgr
assigned
chr
distances
f1
grin
grin1
grin2a
grin2b
grin2c
grin2d
grm1
grm3
grm4
grm5
grm6
linkage
maps
metabotropic
mmyhse
myhse
ppy
rr24
shbg
shr
symbol
wtc
zi