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GRM1
Gene Name
glutamate receptor, metabotropic 1
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Plasma Membrane
Integral Component Of Plasma Membrane
Postsynaptic Density
Dendrite
G-protein Coupled Receptor Dimeric Complex
G-protein Coupled Receptor Homodimeric Complex
Molecular Function
G-protein Coupled Receptor Activity
Protein Binding
Glutamate Receptor Activity
Biological Process
Activation Of MAPKK Activity
Activation Of MAPK Activity
G-protein Coupled Receptor Signaling Pathway
Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway
G-protein Coupled Glutamate Receptor Signaling Pathway
Synaptic Transmission
Locomotory Behavior
Sensory Perception Of Pain
Dimeric G-protein Coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G-protein Coupled Signaling Pathway
Regulation Of Sensory Perception Of Pain
Regulation Of Synaptic Transmission, Glutamatergic
Cellular Response To Electrical Stimulus
Pathways
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
G alpha (q) signalling events
G alpha (q) signalling events
Signaling by GPCR
GPCR downstream signaling
Gastrin-CREB signalling pathway via PKC and MAPK
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
Class C/3 (Metabotropic glutamate/pheromone receptors)
Drugs
L-Glutamic Acid
Acamprosate
4-(1-Amino-1-Carboxy-Ethyl)-Benzoic Acid
Diseases
GWAS
Protein-protein Interactions
12 interactors:
ADORA1
ADRBK1
EFNB2
GAPDH
GPRASP1
GRASP
HOMER1
HOMER2
ITPR1
OPTN
PRKCA
TUBB
Entrez ID
2911
HPRD ID
05129
Ensembl ID
ENSG00000152822
Uniprot IDs
F8W805
Q13255
Q59HC2
PDB IDs
3KS9
Enriched GO Terms of Interacting Partners
?
Defense Response
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Activation Of Phospholipase C Activity
Positive Regulation Of Phospholipase C Activity
Negative Regulation Of Striated Muscle Contraction
Positive Regulation Of Phospholipase Activity
Regulation Of Phospholipase Activity
Negative Regulation Of Signaling
Positive Regulation Of Lipase Activity
Regulation Of Signal Transduction
Chemical Homeostasis Within A Tissue
Behavioral Response To Cocaine
Regulation Of Signaling
Innate Immune Response
Regulation Of Store-operated Calcium Entry
G-protein Coupled Glutamate Receptor Signaling Pathway
Negative Regulation Of Muscle Contraction
Regulation Of Muscle Contraction
Negative Regulation Of Heart Contraction
Epidermal Growth Factor Receptor Signaling Pathway
Response To Stimulus
Fibroblast Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Regulation Of Heart Contraction
Cell Death
Regulation Of Behavior
Cellular Response To Stimulus
Death
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Regulation Of The Force Of Heart Contraction
Negative Regulation Of Signal Transduction
Signal Transduction
Neurotrophin TRK Receptor Signaling Pathway
G-protein Coupled Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Multicellular Organismal Homeostasis
Regulation Of Secretion
Musculoskeletal Movement
Signaling
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Peptidyl-threonine Phosphorylation
Immune Response
Muscle System Process
Regulation Of Hormone Secretion
Response To Cocaine
Cell Surface Receptor Signaling Pathway
Cell Communication
Homeostatic Process
Glutamate Receptor Signaling Pathway
Tagcloud
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asgr
assigned
chr
distances
f1
grin
grin1
grin2a
grin2b
grin2c
grin2d
grm2
grm3
grm4
grm5
grm6
linkage
maps
metabotropic
mmyhse
myhse
ppy
rr24
shbg
shr
symbol
wtc
zi