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GRIA2
Gene Name
glutamate receptor, ionotropic, AMPA 2
Image
Gene Ontology Annotations
Cellular Component
Endoplasmic Reticulum Membrane
Plasma Membrane
Integral Component Of Plasma Membrane
Synaptic Vesicle
Cell Junction
Dendrite
Endocytic Vesicle Membrane
Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Selective Glutamate Receptor Complex
Postsynaptic Membrane
Molecular Function
Ionotropic Glutamate Receptor Activity
Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity
Extracellular-glutamate-gated Ion Channel Activity
Protein Binding
Biological Process
Signal Transduction
Synaptic Transmission
Ion Transmembrane Transport
Ionotropic Glutamate Receptor Signaling Pathway
Synaptic Transmission, Glutamatergic
Pathways
Trafficking of GluR2-containing AMPA receptors
Activation of NMDA receptor upon glutamate binding and postsynaptic events
Activation of AMPA receptors
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity
Trafficking of AMPA receptors
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Unblocking of NMDA receptor, glutamate binding and activation
Transmission across Chemical Synapses
Drugs
L-Glutamic Acid
Butabarbital
Butalbital
Talbutal
Pentobarbital
Secobarbital
Metharbital
Thiopental
Primidone
Methylphenobarbital
Phenobarbital
Quinidine barbiturate
Amobarbital
Aprobarbital
Butethal
Heptabarbital
Hexobarbital
Barbital
Barbituric acid derivative
(S)-Des-Me-Ampa
AMPA
2-Amino-3-(5-Tert-Butyl-3-(Phosphonomethoxy)-4-Isoxazolyl)Propionic Acid
Iodo-Willardiine
Fluoro-Willardiine
Quisqualate
(S)-2-Amino-3-(1,3,5,7-Pentahydro-2,4-Dioxo-Cyclopenta[E]Pyrimidin-1-Yl) Proionic Acid
(S)-ATPA
Dnqx
Bromo-Willardiine
Willardiine
2-Amino-3-(3-Hydroxy-7,8-Dihydro-6h-Cyclohepta[D]-4-Isoxazolyl)Propionic Acid
Aniracetam
THIO-ATPA
N,N\'-[biphenyl-4,4\'-diyldi(2R)propane-2,1-diyl]dimethanesulfonamide
2,3,6A,7,8,9-HEXAHYDRO-11H-[1,4]DIOXINO[2,3-G]PYRROLO[2,1-B][1,3]BENZOXAZIN-11-ONE
(3S)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide
(3R)-3-cyclopentyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide
(3R)-3-cyclopentyl-6-methyl-7-[(4-methylpiperazin-1-yl)sulfonyl]-3,4-dihydro-2H-1,2-benzothiazine 1,1-dioxide
Diseases
GWAS
Protein-protein Interactions
12 interactors:
DRD2
GRIA3
GRIP1
GRIP2
GTF3C2
NSF
PICK1
PRKCA
SDCBP
SPTAN1
SPTBN1
SQSTM1
Entrez ID
2891
HPRD ID
04726
Ensembl ID
ENSG00000120251
Uniprot IDs
I6L997
P42262
PDB IDs
2WJW
2WJX
2XHD
3R7X
3RN8
3RNN
3UA8
Enriched GO Terms of Interacting Partners
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Synaptic Transmission
Cell-cell Signaling
Neuron Development
Neuron Differentiation
Response To External Stimulus
Cell Projection Organization
Protein Localization
Signaling
Protein Localization To Membrane
Regulation Of Vesicle-mediated Transport
Cell Communication
Neuron Projection Development
Positive Regulation Of Receptor Internalization
Membrane Organization
Intracellular Transport
Negative Regulation Of Adenylate Cyclase Activity
Cell Differentiation
Generation Of Neurons
Negative Regulation Of Lyase Activity
Golgi To Plasma Membrane Protein Transport
Negative Regulation Of Cytoskeleton Organization
Neurogenesis
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of CAMP Biosynthetic Process
Axonogenesis
Regulation Of Receptor Internalization
Negative Regulation Of CAMP Metabolic Process
Cell Development
Golgi To Plasma Membrane Transport
Axon Development
Cell Morphogenesis Involved In Neuron Differentiation
Positive Regulation Of Receptor-mediated Endocytosis
Chemotaxis
Negative Regulation Of Nucleotide Metabolic Process
Establishment Of Protein Localization To Membrane
Establishment Of Localization In Cell
Regulation Of Secretion
Neuron Projection Morphogenesis
Locomotion
Golgi Vesicle Transport
Cell Surface Receptor Signaling Pathway
Actin Filament Capping
Cell Morphogenesis Involved In Differentiation
Regulation Of Adenylate Cyclase Activity
Nervous System Development
Negative Regulation Of Actin Filament Depolymerization
Negative Regulation Of Synaptic Transmission
Regulation Of Cyclase Activity
Positive Regulation Of Metabolic Process
Neuron-neuron Synaptic Transmission
Tagcloud
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acutely
arc
camksmall
cyrillicalpha
dioxide
durations
environ
gria1
grin1
grin2a
grin2b
implied
inc
inhalation
inhaled
lifelong
m3
periodicals
pka
pollutant
postsynaptic
presynaptic
psd
so2
synapse
synaptophysin
toxicol
ubiquitous
wiley