SIT1

Gene Name		signaling threshold regulating transmembrane adaptor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Kinase Binding SH2 Domain Binding
	Biological Process	Immune System Process Signal Transduction Regulation Of T Cell Activation
Pathways
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065)
Protein-protein Interactions		7 interactors: CSK FYN GRB2 LCK PTPN11 SYK ZAP70
Entrez ID		27240
HPRD ID		05394
Ensembl ID		ENSG00000137078
Uniprot IDs		Q9Y3P8
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Regulation Of T Cell Activation Positive Regulation Of Cell Activation Peptidyl-tyrosine Autophosphorylation Regulation Of Cell-cell Adhesion Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Regulation Of Lymphocyte Activation Immune Response-regulating Signaling Pathway Regulation Of Cell Activation Leukocyte Migration T Cell Costimulation Regulation Of Cell Adhesion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Innate Immune Response Cell Migration Regulation Of Immune Response Enzyme Linked Receptor Protein Signaling Pathway Cell Motility Positive Regulation Of Immune System Process Antigen Receptor-mediated Signaling Pathway Blood Coagulation Hemostasis Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Platelet Activation Protein Autophosphorylation Locomotion Positive Regulation Of Signal Transduction Regulation Of Body Fluid Levels Immune Response Fc-epsilon Receptor Signaling Pathway Regulation Of Immune System Process Wound Healing Defense Response Positive Regulation Of Immune Response Cell Activation Fc Receptor Signaling Pathway Peptidyl-tyrosine Phosphorylation Movement Of Cell Or Subcellular Component Response To Wounding Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Positive Regulation Of Intracellular Signal Transduction Regulation Of Intracellular Signal Transduction T Cell Receptor Signaling Pathway Phosphatidylinositol-mediated Signaling
Tagcloud ?		bgd1 eai eai1 eai2 eai5 eai6 guadeloupe kelantan kuala lumpur malaysia manila mtbc mys nonthaburi pasteur phylogeographical sit19 sit236 sit256 sit50 sit591 sit745 sit89 sits sitvit2 som spacers spoligo