SAMHD1

Gene Name		SAM domain and HD domain 1
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Gene Ontology Annotations	Cellular Component	Intracellular Nucleus Nucleoplasm Plasma Membrane
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding DGTPase Activity DGTP Binding
	Biological Process	DGTP Catabolic Process Immune Response Cytokine-mediated Signaling Pathway Regulation Of Innate Immune Response DATP Catabolic Process Protein Homotetramerization Defense Response To Virus Type I Interferon Signaling Pathway
Pathways		Interferon Signaling Cytokine Signaling in Immune system Interferon alpha/beta signaling
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: APP FBXO25 RBX1 TIRAP
Entrez ID		25939
HPRD ID		08418
Ensembl ID		ENSG00000101347
Uniprot IDs		Q59H15 Q9Y3Z3
PDB IDs		2E8O 3U1N
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Interleukin-15 Production Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production TIRAP-dependent Toll-like Receptor 4 Signaling Pathway Notch Signaling Pathway Regulation Of Protein Binding Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Synaptic Growth At Neuromuscular Junction Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Collateral Sprouting In Absence Of Injury Positive Regulation Of Chemokine (C-X-C Motif) Ligand 2 Production Regulation Of Binding Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Axon Choice Point Recognition Neuron Remodeling Positive Regulation Of Protein Homodimerization Activity Protein Neddylation 3'-UTR-mediated MRNA Stabilization Cellular Response To Bacterial Lipopeptide Positive Regulation Of Toll-like Receptor Signaling Pathway Posttranscriptional Regulation Of Gene Expression Cellular Response To Lipoteichoic Acid Positive Regulation Of Interleukin-6 Biosynthetic Process Cellular Copper Ion Homeostasis Regulation Of Protein Homodimerization Activity Protein Ubiquitination Regulation Of Interleukin-6 Biosynthetic Process Copper Ion Homeostasis Suckling Behavior Protein Modification By Small Protein Conjugation Regulation Of Growth Positive Regulation Of Neutrophil Chemotaxis SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Granulocyte Chemotaxis MRNA Stabilization Negative Regulation Of Growth Of Symbiont In Host Regulation Of Neutrophil Chemotaxis Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of Neutrophil Migration Positive Regulation Of Interleukin-8 Production Mating Behavior Regulation Of Signal Transduction Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Granulocyte Chemotaxis
Tagcloud ?		cct5 cd68 ddx5 enterovirus ft1dm fulminant helicase hnrnph1 hspa1l infiltrated inflamed insulitis iqgap1 lamin lcp1 lmnb1 microdissection moesin msn pdg phosphogluconate phosphorylase plastin protein1 psme1 serpin serpinb6 tymp wars