USP49

Gene Name		ubiquitin specific peptidase 49
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding Histone Binding
	Biological Process	MRNA Splicing, Via Spliceosome Protein Deubiquitination Histone H2B Conserved C-terminal Lysine Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS		Mean corpuscular hemoglobin ( 20139978) Mean corpuscular volume ( 23263863 20139978) Red blood cell count ( 20139978)
Protein-protein Interactions		6 interactors: HIST2H2BE MED17 MED18 MED8 RBCK1 TRIM35
Entrez ID		25862
HPRD ID		10075
Ensembl ID		ENSG00000164663
Uniprot IDs		Q70CQ1
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?		affects cotranscriptional deubiquitinase deubiquitinates deubiquitination dramatically eukaryotes exons h2b identifies intronic knockdown like1 modulated nascent nucleosome peptidase purification relatively ruvb rvb1 splicing sug1 u1a u2b ubiquitination uh2b uncovers upstream