ALOX5AP

Gene Name		arachidonate 5-lipoxygenase-activating protein
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Gene Ontology Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Nuclear Membrane
	Molecular Function	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Glutathione Peroxidase Activity Protein Binding Enzyme Activator Activity Protein N-terminus Binding Arachidonic Acid Binding
	Biological Process	Leukotriene Metabolic Process Arachidonic Acid Metabolic Process Leukotriene Biosynthetic Process Lipoxygenase Pathway Positive Regulation Of Catalytic Activity Small Molecule Metabolic Process Protein Homotrimerization Cellular Response To Calcium Ion Lipoxin Metabolic Process
Pathways		Arachidonic acid metabolism Synthesis of 5-eicosatetraenoic acids Metabolism of lipids and lipoproteins Synthesis of Lipoxins (LX) Synthesis of Leukotrienes (LT) and Eoxins (EX)
Drugs
Diseases
GWAS		Non-word repetition ( 23738518)
Protein-protein Interactions		3 interactors: ALOX5 CLIC1 LTC4S
Entrez ID		241
HPRD ID		04742
Ensembl ID		ENSG00000132965
Uniprot IDs		P20292
PDB IDs		2Q7M 2Q7R
Enriched GO Terms of Interacting Partners?		Lipoxin Metabolic Process Lipoxygenase Pathway Leukotriene Biosynthetic Process Leukotriene Metabolic Process Icosanoid Biosynthetic Process Unsaturated Fatty Acid Biosynthetic Process Arachidonic Acid Metabolic Process Icosanoid Metabolic Process Unsaturated Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Leukotriene Production Involved In Inflammatory Response Fatty Acid Metabolic Process Lipid Biosynthetic Process Monocarboxylic Acid Metabolic Process Production Of Molecular Mediator Involved In Inflammatory Response Regulation Of Mitochondrial Membrane Potential Cellular Lipid Metabolic Process Platelet Aggregation Carboxylic Acid Metabolic Process Organic Acid Metabolic Process Lipid Metabolic Process Positive Regulation Of Osteoblast Differentiation Oxidation-reduction Process Positive Regulation Of Ossification Chloride Transmembrane Transport Regulation Of Osteoblast Differentiation Chloride Transport
Tagcloud ?		acat acyltransferase arachidonate ath atherosclerotic cbs cysthathionenine deceased gathered genomelab gexp hcats irs1 lcat ldlr lecithin lipoxygenase lpl malaysian metallopeptidase methylenetetrahydrofolate mmp9 mortem mthfr ncat predetermined tgfbr2 thbd thrombomodulin