OTUD3

Gene Name		OTU deubiquitinase 3
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Gene Ontology Annotations	Cellular Component
	Molecular Function	Ubiquitin-specific Protease Activity
	Biological Process	Proteolysis Protein K11-linked Deubiquitination Protein K6-linked Deubiquitination
Pathways
Drugs
Diseases
GWAS		Ulcerative colitis ( 19915572 20228798 20228799 19122664 23511034)
Protein-protein Interactions		1 interactors: UBC
Entrez ID		23252
HPRD ID		19417
Ensembl ID		ENSG00000169914
Uniprot IDs		Q5T2D3
PDB IDs		4BOU
Enriched GO Terms of Interacting Partners?		Viral Protein Processing Notch Receptor Processing Virion Assembly Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Glycogen Biosynthetic Process Intracellular Transport Of Virus Cellular Polysaccharide Biosynthetic Process Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Polysaccharide Biosynthetic Process Negative Regulation Of Type I Interferon Production Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of DNA-templated Transcription In Response To Stress DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Toll-like Receptor 2 Signaling Pathway Signal Transduction Involved In DNA Damage Checkpoint Toll-like Receptor 9 Signaling Pathway Signal Transduction Involved In Cell Cycle Checkpoint Glycogen Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Transferase Activity Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Ligase Activity Positive Regulation Of Type I Interferon Production DNA Damage Response, Signal Transduction By P53 Class Mediator Toll-like Receptor 4 Signaling Pathway Regulation Of ERBB Signaling Pathway Polysaccharide Metabolic Process Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Tagcloud ?		13q12 16q24 1p36 21q21 9p24 arm bonferroni caucasian caucasians corrected crohn ethnicity histocompatibility korean loci marginal pla2g2e rnf186 rs1297265 rs16940186 rs17085007 rs4654903 rs9271366 sharing tend top ube2l3 uc ulcerative