TBC1D1

Gene Name		TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
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Gene Ontology Annotations	Cellular Component	Nucleus Cytosol
	Molecular Function	Rab GTPase Activator Activity Protein Binding
	Biological Process	Positive Regulation Of Rab GTPase Activity Regulation Of Protein Localization Membrane Organization Regulation Of Cilium Assembly
Pathways		Translocation of GLUT4 to the plasma membrane
Drugs
Diseases
GWAS		Crohn's disease ( 23266558) Periodontal microbiota ( 22699663)
Protein-protein Interactions		4 interactors: GABARAPL1 MAP1LC3A SMAD2 YWHAG
Entrez ID		23216
HPRD ID		18161
Ensembl ID		ENSG00000065882
Uniprot IDs		B9A6J6 Q6PJJ8 Q86TI0 Q8NC59
PDB IDs		3QYE
Enriched GO Terms of Interacting Partners?		Nucleophagy Mitochondrion Degradation Organelle Disassembly Autophagic Vacuole Assembly Macroautophagy Vacuole Organization Membrane Fusion Membrane Organization Cellular Response To Starvation Autophagy Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Cellular Response To Nutrient Levels Response To Starvation Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Zygotic Specification Of Dorsal/ventral Axis Cellular Response To Extracellular Stimulus Positive Regulation Of Mesoderm Development Primary MiRNA Processing Regulation Of Nodal Signaling Pathway Common-partner SMAD Protein Phosphorylation Positive Regulation Of Activin Receptor Signaling Pathway Mitochondrion Organization Response To Nutrient Levels SMAD Protein Complex Assembly Cellular Component Assembly Paraxial Mesoderm Morphogenesis Response To Extracellular Stimulus Organelle Assembly Nodal Signaling Pathway Cellular Response To Nitrogen Starvation Cell Communication Production Of MiRNAs Involved In Gene Silencing By MiRNA Embryonic Foregut Morphogenesis Foregut Morphogenesis Regulation Of Activin Receptor Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Paraxial Mesoderm Development Response To Cholesterol Dorsal/ventral Axis Specification Pericardium Development Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Activin Receptor Signaling Pathway Positive Regulation Of Epithelial To Mesenchymal Transition Signal Transduction Involved In Regulation Of Gene Expression Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Gene Silencing By MiRNA Cellular Response To Stimulus Cellular Response To DsRNA Positive Regulation Of BMP Signaling Pathway Insulin Secretion
Tagcloud ?		adaptor alanine appl1 appl2 bar conditional diminishes elusive evoked fine glut4 gtpase homolog hyperglycemia likewise muscles myotubes partner potentiates rab serine skeletal stimulates substitution suppresses suppressive threonine tune uptake