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NLRP1
Gene Name
NLR family, pyrin domain containing 1
Image
Gene Ontology Annotations
Cellular Component
Intracellular
Nucleus
Cytosol
NLRP1 Inflammasome Complex
Molecular Function
Protein Binding
ATP Binding
Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process
Enzyme Binding
Protein Domain Specific Binding
Biological Process
Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Response To Muramyl Dipeptide
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Defense Response To Bacterium
Innate Immune Response
Positive Regulation Of Interleukin-1 Beta Secretion
Regulation Of Inflammatory Response
Neuron Apoptotic Process
Pathways
Inflammasomes
The NLRP1 inflammasome
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
Innate Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions
9 interactors:
APAF1
BCL2
BCL2L1
CASP1
CASP2
CASP5
CASP9
NOD1
PYCARD
Entrez ID
22861
HPRD ID
07364
Ensembl ID
ENSG00000091592
Uniprot IDs
E9PE50
Q9C000
Q9H5Z7
PDB IDs
1PN5
3KAT
4IFP
Enriched GO Terms of Interacting Partners
?
Apoptotic Process
Programmed Cell Death
Cell Death
Death
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Regulation Of Apoptotic Process
Intrinsic Apoptotic Signaling Pathway
Regulation Of Cell Death
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Cysteine-type Endopeptidase Activity
Protein Processing
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Activation Of Cysteine-type Endopeptidase Activity
Zymogen Activation
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Cysteine-type Endopeptidase Activity
Positive Regulation Of Endopeptidase Activity
Apoptotic Signaling Pathway
Response To Biotic Stimulus
Positive Regulation Of Peptidase Activity
Regulation Of Endopeptidase Activity
Regulation Of Peptidase Activity
Intracellular Receptor Signaling Pathway
Positive Regulation Of Apoptotic Signaling Pathway
Response To External Stimulus
Positive Regulation Of Interleukin-1 Beta Secretion
Positive Regulation Of Proteolysis
Positive Regulation Of Interleukin-1 Secretion
Regulation Of Proteolysis
Positive Regulation Of Signal Transduction
Regulation Of Autophagy
Response To Other Organism
Regulation Of Interleukin-1 Beta Secretion
Innate Immune Response
Positive Regulation Of Interleukin-1 Beta Production
Positive Regulation Of Interleukin-1 Production
Regulation Of Mitochondrial Membrane Potential
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Intracellular Signal Transduction
Regulation Of Interleukin-1 Beta Production
Response To Abiotic Stimulus
Positive Regulation Of Cellular Protein Metabolic Process
Neuron Apoptotic Process
Pyroptosis
Regulation Of Neuron Apoptotic Process
Positive Regulation Of Protein Metabolic Process
Tagcloud
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ancient
archaea
autoproteolysis
autoproteolytic
card8
deteriorated
extend
fam171
fiind
gpcr
gpcrs
gps
hfs
hlt
lrr
nacht
nucleoporin98
nup98
occluden
origination
polycystic
precedes
pyd
searches
subdomain
unc5c
upa
zonula
zu5