CYB5R3

Gene Name		cytochrome b5 reductase 3
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Particle Hemoglobin Complex Membrane Extracellular Vesicular Exosome
	Molecular Function	Cytochrome-b5 Reductase Activity, Acting On NAD(P)H AMP Binding ADP Binding Flavin Adenine Dinucleotide Binding NAD Binding FAD Binding
	Biological Process	Cholesterol Biosynthetic Process Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process Blood Circulation L-ascorbic Acid Metabolic Process Small Molecule Metabolic Process Oxidation-reduction Process
Pathways		Metabolism of vitamins and cofactors Defective CD320 causes methylmalonic aciduria Defective GIF causes intrinsic factor deficiency Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Vitamin C (ascorbate) metabolism Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective MMAA causes methylmalonic aciduria type cblA Defective CUBN causes hereditary megaloblastic anemia 1 Defective AMN causes hereditary megaloblastic anemia 1 Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Defective TCN2 causes hereditary megaloblastic anemia Defects in cobalamin (B12) metabolism Defects in vitamin and cofactor metabolism
Drugs		NADH Nicotinamide-Adenine-Dinucleotide Flavin-Adenine Dinucleotide
Diseases
GWAS
Protein-protein Interactions		4 interactors: CYB5A CYCS HBG2 SPP1
Entrez ID		1727
HPRD ID		08942
Ensembl ID		ENSG00000100243
Uniprot IDs		P00387
PDB IDs		1M91 1UMK
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Mitochondrial Electron Transport, Cytochrome C To Oxygen Negative Regulation Of Collateral Sprouting Negative Regulation Of Axon Regeneration Mitochondrial Electron Transport, Ubiquinol To Cytochrome C L-ascorbic Acid Metabolic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C
Tagcloud ?