CCDC50

Description		coiled-coil domain containing 50
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GO Annotations	Cellular Component	Cytoplasm Cytosol Ciliary Basal Body
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding
	Biological Process	Sensory Perception Of Sound
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease biomarkers ( 23562540) Lung cancer in never smokers ( 28604730)
Novel Interacting Genes		1 novel interacting genes: NPHP3
Interacting Genes		14 interacting genes: ARRDC3 HNRNPA1 IFIH1 MAP1LC3B MAVS RIGI RIPK1 RNF26 RNF8 RPS3A SH3GL1 STING1 TNFAIP3 UBC
Entrez ID		152137
HPRD ID		06463
Ensembl ID		ENSG00000152492
Uniprot IDs		Q8IVM0
PDB IDs		6LAN
Enriched GO Terms of Interacting Partners?		Regulation Of Defense Response To Virus Positive Regulation Of Response To Cytokine Stimulus Cellular Response To DsRNA Cellular Response To Exogenous DsRNA Cytoplasmic Pattern Recognition Receptor Signaling Pathway Response To Exogenous DsRNA Positive Regulation Of Interferon-beta Production Regulation Of Defense Response To Virus By Host Response To DsRNA Regulation Of Type I Interferon Production Ubiquitin Protein Ligase Binding Regulation Of Interferon-beta Production Pattern Recognition Receptor Signaling Pathway Regulation Of Tumor Necrosis Factor Production Innate Immune Response-activating Signaling Pathway Antiviral Innate Immune Response Activation Of Innate Immune Response Positive Regulation Of Type I Interferon Production Intracellular Receptor Signaling Pathway Positive Regulation Of Defense Response Positive Regulation Of Interferon-alpha Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Regulation Of Cytokine Production Regulation Of Defense Response Positive Regulation Of Defense Response To Virus By Host Identical Protein Binding Detection Of Virus Positive Regulation Of Innate Immune Response Regulation Of Interleukin-6 Production Single-stranded RNA Binding Immune Response-activating Signaling Pathway Regulation Of Type III Interferon Production Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Myeloid Dendritic Cell Cytokine Production MRNA Transcription Immune Response-regulating Signaling Pathway Positive Regulation Of Interleukin-8 Production Activation Of Immune Response Positive Regulation Of Cytokine-mediated Signaling Pathway Regulation Of Innate Immune Response Signaling Adaptor Activity Positive Regulation Of Dendritic Cell Cytokine Production Positive Regulation Of Cytokine Production Regulation Of Interleukin-8 Production Positive Regulation Of Interleukin-6 Production Defense Response To Virus Regulation Of Dendritic Cell Cytokine Production Positive Regulation Of Type I Interferon-mediated Signaling Pathway Positive Regulation Of Immune System Process
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