HAPLN1

Gene Name		hyaluronan and proteoglycan link protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Extracellular Matrix
	Molecular Function	Extracellular Matrix Structural Constituent Hyaluronic Acid Binding
	Biological Process	Skeletal System Development Cell Adhesion Central Nervous System Development Extracellular Matrix Organization
Pathways		ECM proteoglycans
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 22138694) Prostate cancer ( 17903305) Visceral fat ( 22589738)
Protein-protein Interactions		8 interactors: ACAN APP MMP10 MMP2 MMP3 MMP7 MMP9 VCAN
Entrez ID		1404
HPRD ID		00275
Ensembl ID		ENSG00000145681
Uniprot IDs		P10915
PDB IDs
Enriched GO Terms of Interacting Partners?		Extracellular Matrix Organization Extracellular Structure Organization Extracellular Matrix Disassembly Collagen Catabolic Process Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Multicellular Organismal Metabolic Process Catabolic Process Proteolysis Protein Metabolic Process Skeletal System Development Endodermal Cell Differentiation Ossification Endoderm Formation Proteoglycan Biosynthetic Process Glycosaminoglycan Catabolic Process Cellular Response To Amino Acid Stimulus Axon Guidance Embryo Implantation Antibacterial Peptide Secretion Antibacterial Peptide Biosynthetic Process Endoderm Development Nervous System Development Locomotion Ephrin Receptor Signaling Pathway Glycosaminoglycan Biosynthetic Process Proteoglycan Metabolic Process Axonogenesis Response To Amino Acid Synaptic Growth At Neuromuscular Junction Axon Development Cell Recognition Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Cell Migration Chemotaxis Formation Of Primary Germ Layer Movement Of Cell Or Subcellular Component Regulation Of Cell Motility Collateral Sprouting In Absence Of Injury Neuron Projection Morphogenesis Regulation Of Protein Binding Regulation Of Locomotion Regulation Of Cellular Component Movement Organ Development Positive Regulation Of Receptor Binding Negative Regulation Of Hydrogen Peroxide Metabolic Process Neurogenesis Cell Morphogenesis Involved In Differentiation Cellular Response To Acid Chemical Glycosaminoglycan Metabolic Process
Tagcloud ?		aabs ac adenocarcinoma antigens autoantibodies autoantigens autologous bigh3 coincidently comparative comprised consists dimensional discover expressions hyaluronan ig immunoblotting immunostaining link proteoglycan sera sero spots stroma surrounding thirty transforming tumor