EDARADD

Gene Name		EDAR-associated death domain
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm
	Molecular Function
	Biological Process	Hair Follicle Development Signal Transduction Cell Differentiation Odontogenesis Of Dentin-containing Tooth Trachea Gland Development
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		10 interactors: EDAR RNF111 SDCBP SHPRH SUMO1 SUMO1P1 TRAF2 TRAF6 UBE2I WDYHV1
Entrez ID		128178
HPRD ID		05965
Ensembl ID		ENSG00000186197
Uniprot IDs		Q8WWZ3
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Modification By Small Protein Conjugation Protein Polyubiquitination Protein Ubiquitination Positive Regulation Of Signal Transduction Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Signal Transduction Regulation Of Immunoglobulin Secretion Positive Regulation Of JNK Cascade Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Signaling Positive Regulation Of T Cell Cytokine Production Cellular Protein Modification Process Regulation Of JNK Cascade Regulation Of Stress-activated MAPK Cascade Regulation Of T Cell Cytokine Production Protein Sumoylation Activation Of NF-kappaB-inducing Kinase Activity Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of NIK/NF-kappaB Signaling Protein K63-linked Ubiquitination Positive Regulation Of Interleukin-2 Production NIK/NF-kappaB Signaling Regulation Of Innate Immune Response Regulation Of NIK/NF-kappaB Signaling Protein Autoubiquitination Regulation Of Binding Regulation Of Protein Localization Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cytokine Production Involved In Immune Response Cellular Protein Metabolic Process I-kappaB Kinase/NF-kappaB Signaling TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of JUN Kinase Activity Regulation Of Cytokine Production Involved In Immune Response Regulation Of Cellular Localization Positive Regulation Of SUMO Transferase Activity Toll-like Receptor 4 Signaling Pathway Regulation Of JUN Kinase Activity Regulation Of DNA Binding Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of MAPK Cascade Cytokine-mediated Signaling Pathway Positive Regulation Of Protein Metabolic Process Positive Regulation Of T Cell Mediated Immunity Odontogenesis Of Dentin-containing Tooth Toll-like Receptor Signaling Pathway
Tagcloud ?		chin craniofacial ectodermal ectodysplasin eda1 fuller hed hypohidrotic hypoplasia landmarks malformed mandible midface midfacial morphologies morphometrics narrower nose philtrum pointed proportionally protrusive refine rounded sweat umbrella xlhed