SOCS4

Gene Name		suppressor of cytokine signaling 4
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm
	Molecular Function	Protein Kinase Inhibitor Activity
	Biological Process	Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Protein Ubiquitination Cytokine-mediated Signaling Pathway Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Intracellular Signal Transduction Regulation Of Growth Negative Regulation Of JAK-STAT Cascade
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: EGFR MDFIC NR4A1 SPRY1 VWF
Entrez ID		122809
HPRD ID		18084
Ensembl ID		ENSG00000180008
Uniprot IDs		Q5H9R6 Q8WXH5
PDB IDs		2IZV
Enriched GO Terms of Interacting Partners?		Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of MAP Kinase Activity Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of MAPK Cascade Alkanesulfonate Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Kinase Activity Phosphatidylinositol-mediated Signaling Regulation Of Protein Metabolic Process Regulation Of Kinase Activity Positive Regulation Of Epithelial Cell Proliferation Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation Liver Development Regulation Of Catalytic Activity Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Protein Metabolic Process Regulation Of Protein Import Into Nucleus Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Steroid Hormone Stimulus Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of ERK1 And ERK2 Cascade Placenta Development Response To Fibroblast Growth Factor Regulation Of Protein Localization To Nucleus Regulation Of Nucleocytoplasmic Transport Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Activation Of Phospholipase A2 Activity Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of MAP Kinase Activity Regulation Of Protein Phosphorylation Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway MAPK Cascade Positive Regulation Of Phospholipase A2 Activity Lung Development Respiratory Tube Development Organ Development Response To Cobalamin Response To UV-A Regulation Of Intracellular Protein Transport Fc Receptor Signaling Pathway Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Neurotrophin TRK Receptor Signaling Pathway
Tagcloud ?		abovementioned activators exceptions expressions glucocorticosteroids jak jak1 jak3 jaks leukocytes nephrotic ns socs1 socs2 socs3 socs5 srns ssns stat stat2 stat6 stats steroid steroids suppressors transducers tyk2 unfavorable