CNTRL

Gene Name		centriolin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Membrane
	Molecular Function	Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Cell Division
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: MAP3K4 MAPK6 TRADD UBC
Entrez ID		11064
HPRD ID		05691
Ensembl ID		ENSG00000119397
Uniprot IDs		Q7Z7A1
PDB IDs
Enriched GO Terms of Interacting Partners?		MAPK Cascade Signal Transduction By Phosphorylation Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of NF-kappaB Transcription Factor Activity Activation Of MAPK Activity Male Germ-line Sex Determination Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of MAP Kinase Activity Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Primary Sex Determination Positive Regulation Of Protein Metabolic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Signal Transduction Protein Processing Activation Of Protein Kinase Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Regulation Of MAP Kinase Activity Positive Regulation Of Proteolysis Positive Regulation Of Catalytic Activity Chorionic Trophoblast Cell Differentiation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Chorion Development Apoptotic Signaling Pathway Positive Regulation Of P38MAPK Cascade Regulation Of Intracellular Signal Transduction Positive Regulation Of Hair Follicle Development Viral Protein Processing Phosphorylation Intracellular Signal Transduction Response To UV-C Positive Regulation Of MAPK Cascade Cytokine-mediated Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Kinase Activity Signal Transduction Positive Regulation Of Kinase Activity Male Sex Determination Regulation Of P38MAPK Cascade Regulation Of Hair Follicle Development Regulation Of Protein Metabolic Process Protein Metabolic Process Positive Regulation Of Transferase Activity Signaling Cellular Response To Cytokine Stimulus Cell Communication Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Regulation Of Hair Cycle Notch Receptor Processing
Tagcloud ?		ab abi animals bmd colitic colitis dosed dosing elastic experiment extrinsic femoral femur femurs fracture halted investigates mechanical modulus neutralizing noncolitic osteoblast osteoclast prophylactically resorption scl sclerostin ultimate worse