HYOU1

Description		hypoxia up-regulated 1
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Lumen Smooth Endoplasmic Reticulum Focal Adhesion Membrane Endoplasmic Reticulum Chaperone Complex Extracellular Exosome Endocytic Vesicle Lumen
	Molecular Function	Nucleotide Binding Adenyl-nucleotide Exchange Factor Activity Protein Binding ATP Binding Unfolded Protein Binding Protein-folding Chaperone Binding ATP-dependent Protein Folding Chaperone
	Biological Process	Response To Ischemia Protein Folding Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Response To Stress Response To Endoplasmic Reticulum Stress Negative Regulation Of Apoptotic Process Cellular Response To Hypoxia Regulation Of Cellular Response To Stress Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Scavenging by Class F Receptors Scavenging by Class F Receptors XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Post bronchodilator FEV1/FVC ratio ( 26634245) Post-bronchodilator lung function in asthma (FVC) ( 32989782)
Novel Interacting Genes		11 novel interacting genes: CADM1 DPYSL3 IL1R1 IL1RL1 INPPL1 NXPE4 PPP2R1B RBM7 TAGLN TMEM245 TP53BP2
Interacting Genes		4 interacting genes: CDC42 CEBPA LINC01554 SEL1L
Entrez ID		10525
HPRD ID		03448
Ensembl ID		ENSG00000149428
Uniprot IDs		A0A384P5T6 A0A494C039 A0A8Q3SHG4 B3KXH0 B7Z602 B7Z766 Q6IN67 Q9Y4L1
PDB IDs
Enriched GO Terms of Interacting Partners?		Macrophage Differentiation Interleukin-1 Receptor Activity NAD+ Nucleosidase Activity, Cyclic ADP-ribose Generating SH3 Domain Binding Positive Regulation Of Filopodium Assembly Myeloid Leukocyte Differentiation Positive Regulation Of Macrophage Activation
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