KRT72 and TAMALIN

		KRT72	TAMALIN
Description		keratin 72	trafficking regulator and scaffold protein tamalin
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament Extracellular Exosome	Cytoplasm Plasma Membrane Postsynaptic Density Membrane Synapse Postsynaptic Membrane Perinuclear Region Of Cytoplasm Glutamatergic Synapse
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis	PDZ Domain Binding Small GTPase Binding Identical Protein Binding
	Biological Process	Keratinization Intermediate Filament Organization	Signal Transduction Regulation Of Postsynaptic Neurotransmitter Receptor Internalization
Pathways		Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		High density lipoprotein cholesterol levels ( 30498476)
Interacting Genes		33 interacting genes: BCDIN3D BLOC1S6 HSPB1 KRT13 KRT14 KRT15 KRT16 KRT17 KRT18 KRT19 KRT20 KRT24 KRT25 KRT26 KRT27 KRT28 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT40 KRT74 KRT78 KRT80 LARP4 MYL6B SP7 TAMALIN UBC	13 interacting genes: ACE2 CYTH3 DLG4 DOCK1 FYN GABBR2 GRM1 GRM2 GRM3 GRM5 KRT72 RPS6KA1 SRC
Entrez ID		140807	160622
HPRD ID		09746	17077
Ensembl ID		ENSG00000170486	ENSG00000161835
Uniprot IDs		B4DXK4 Q14CN4	Q7Z6J2
PDB IDs			2PNT
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Intermediate Filament Structural Molecule Activity Supramolecular Fiber Organization Morphogenesis Of An Epithelium Epithelial Cell Differentiation Cytoskeleton Organization Tissue Morphogenesis Cytoskeleton Organelle Organization Anatomical Structure Morphogenesis Extracellular Exosome Cytosol Cell Differentiation Cellular Developmental Process Hair Cycle Intermediate Filament Cytoskeleton Structural Constituent Of Cytoskeleton Developmental Process Keratinization Epidermis Development Hair Follicle Morphogenesis Cornified Envelope Tissue Development Hair Cycle Process Cell Periphery Keratin Filament Binding Negative Regulation Of Protein Kinase C Signaling Bradykinin Biosynthetic Process Circadian Sleep/wake Cycle	Glutamate Receptor Signaling Pathway G Protein-coupled Glutamate Receptor Signaling Pathway Adenylate Cyclase-inhibiting G Protein-coupled Glutamate Receptor Signaling Pathway Glutamate Receptor Activity Chemical Synaptic Transmission Scaffold Protein Binding Trans-synaptic Signaling Synaptic Signaling Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Postsynaptic Membrane Negative Regulation Of Adenylate Cyclase Activity Glutamatergic Synapse Cell-cell Signaling Neuron Projection Astrocyte Projection Signaling Cell Communication Regulation Of Synaptic Transmission, Glutamatergic G Protein-coupled Receptor Signaling Pathway Neurotransmitter Receptor Activity Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Group II Metabotropic Glutamate Receptor Activity Modulation Of Chemical Synaptic Transmission G Protein-coupled Receptor Activity Involved In Regulation Of Postsynaptic Membrane Potential G Protein-coupled Receptor Activity Adenylate Cyclase Inhibiting G Protein-coupled Glutamate Receptor Activity Phospholipase C-activating G Protein-coupled Glutamate Receptor Signaling Pathway Dendrite Regulation Of Cell Communication Regulation Of Signaling Plasma Membrane Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Cell Surface Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Phospholipase Activator Activity Postsynaptic Density Schaffer Collateral - CA1 Synapse Regulation Of Signal Transduction Postsynaptic Density Membrane Protein Tyrosine Kinase Activator Activity Amino Acid Transport Stimulatory C-type Lectin Receptor Signaling Pathway Phospholipase Binding Cellular Response To Lectin Signal Transduction Cellular Response To Platelet-derived Growth Factor Stimulus Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc Receptor Mediated Stimulatory Signaling Pathway Response To Platelet-derived Growth Factor Dendritic Spine
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