KRT72 and KRT78

		KRT72	KRT78
Description		keratin 72	keratin 78
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament Extracellular Exosome	Extracellular Space Cytosol Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Protein Binding Structural Constituent Of Skin Epidermis	Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Keratinization Intermediate Filament Organization	Keratinization Intermediate Filament Organization
Pathways		Keratinization Formation of the cornified envelope	Keratinization Formation of the cornified envelope Differentiation of Keratinocytes in Interfollicular Epidermis in Mammalian Skin
Drugs
Diseases
GWAS		High density lipoprotein cholesterol levels ( 30498476)	Aspartate aminotransferase levels ( 33547301) Gamma glutamyl transferase levels ( 29403010)
Interacting Genes		33 interacting genes: BCDIN3D BLOC1S6 HSPB1 KRT13 KRT14 KRT15 KRT16 KRT17 KRT18 KRT19 KRT20 KRT24 KRT25 KRT26 KRT27 KRT28 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT40 KRT74 KRT78 KRT80 LARP4 MYL6B SP7 TAMALIN UBC	24 interacting genes: C14orf119 KRT13 KRT14 KRT15 KRT16 KRT19 KRT24 KRT25 KRT26 KRT27 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRT72 SRPK2 TRIM54 UCHL5
Entrez ID		140807	196374
HPRD ID		09746	17171
Ensembl ID		ENSG00000170486	ENSG00000170423
Uniprot IDs		B4DXK4 Q14CN4	Q8N1N4
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Intermediate Filament Structural Molecule Activity Supramolecular Fiber Organization Morphogenesis Of An Epithelium Epithelial Cell Differentiation Cytoskeleton Organization Tissue Morphogenesis Cytoskeleton Organelle Organization Anatomical Structure Morphogenesis Extracellular Exosome Cytosol Cell Differentiation Cellular Developmental Process Hair Cycle Intermediate Filament Cytoskeleton Structural Constituent Of Cytoskeleton Developmental Process Keratinization Epidermis Development Hair Follicle Morphogenesis Cornified Envelope Tissue Development Hair Cycle Process Cell Periphery Keratin Filament Binding Negative Regulation Of Protein Kinase C Signaling Bradykinin Biosynthetic Process Circadian Sleep/wake Cycle	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Morphogenesis Of An Epithelium Supramolecular Fiber Organization Epithelial Cell Differentiation Tissue Morphogenesis Cytoskeleton Organization Cytoskeleton Anatomical Structure Morphogenesis Organelle Organization Cell Differentiation Cellular Developmental Process Extracellular Exosome Cytosol Developmental Process Hair Cycle Epidermis Development Structural Constituent Of Cytoskeleton Tissue Development Hair Follicle Morphogenesis Intermediate Filament Cytoskeleton Cornified Envelope Protein Binding Keratinocyte Differentiation Keratinization Terminal Web Hair Cycle Process Nuclear Speck Organization
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