GABARAP and ATG101

Number of citations of the paper that reports this interaction (PubMedID 24100292)
45

Data Source:
BioGRID (two hybrid)

		GABARAP	ATG101
Description		GABA type A receptor-associated protein	autophagy related 101
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GO Annotations	Cellular Component	Golgi Membrane Autophagosome Membrane Cytoplasm Lysosome Autophagosome Smooth Endoplasmic Reticulum Golgi Apparatus Cytosol Cytoskeleton Microtubule Microtubule Associated Complex Plasma Membrane Axoneme Endomembrane System Actin Cytoskeleton Membrane Cytoplasmic Vesicle Sperm Midpiece GABA-ergic Synapse	Phagophore Assembly Site Cytoplasm Endoplasmic Reticulum Membrane Cytosol Atg1/ULK1 Kinase Complex
	Molecular Function	Protein Binding Phospholipid Binding Microtubule Binding Phosphatidylethanolamine Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding GABA Receptor Binding	Protein Binding Protein Kinase Binding Identical Protein Binding Protein-containing Complex Binding
	Biological Process	Autophagosome Assembly Microtubule Cytoskeleton Organization Mitophagy Protein Targeting Autophagy Apoptotic Process Cellular Response To Nitrogen Starvation Chemical Synaptic Transmission Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Protein Transport Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Rac Protein Signal Transduction Autophagosome Maturation Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Positive Regulation Of Protein K48-linked Ubiquitination	Autophagosome Assembly Autophagy Negative Regulation Of Cell Population Proliferation Positive Regulation Of Autophagy
Pathways		Macroautophagy TBC/RABGAPs	Macroautophagy
Drugs
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 33972514)
Interacting Genes		75 interacting genes: AMBRA1 ANK2 ANK3 APPL1 ATG101 ATG13 ATG3 ATG4B ATG4C ATG4D ATG7 ATXN3 AZI2 BICC1 BIRC6 CARS2 CCT2 CDC37 CUL3 DMPK DVL2 FLCN G3BP1 GABRG1 GABRG2 GABRG3 GJA1 GPHN HDAC5 KBTBD7 KDR LMNB1 MAP4K2 MAPK15 MEFV MIB1 MLH1 MPC1 MTX1 MYBPC1 MYBPC2 NBR1 NCOR1 NEDD4 NEK9 NSF NUFIP2 OPTN PCM1 PGS1 PKP4 PRKCZ RB1CC1 RESF1 SAMM50 SEC62 SNX18 SRPK1 SRPK2 STK3 TAX1BP1 TBC1D25 TFRC TLE5 TNIP1 TP53INP1 TRIM21 TRIM25 TRIM32 TSR2 TTN TUBB3 ULK1 ULK2 VPS28	6 interacting genes: ATG13 ATG4A CSNK2B GABARAP MYL3 PTCH1
Entrez ID		11337	60673
HPRD ID		05496	08566
Ensembl ID		ENSG00000170296	ENSG00000123395
Uniprot IDs		O95166 Q6IAW1	Q9BSB4
PDB IDs		1GNU 1KLV 1KM7 1KOT 3D32 3DOW 3WIM 4XC2 5DPS 6HB9 6HOG 6HOH 6HOJ 6HOK 6HYL 6HYM 6HYN 6HYO 6YOP 7AA8 7BRQ 7BRT 7BRU 7BV4 7EA7 7LSW 7LT6 7VEC 7VED 7YO9 7ZKR 7ZL7 8AFI 8S1M 8T2M 8T2N 8T31 8T32 8T33 8W6A	4WZG 5C50 5XUY 5XV1 5XV3 5XV4 5XV6 8DO8
Enriched GO Terms of Interacting Partners?		Autophagosome Autophagosome Assembly Autophagosome Organization Nucleophagy Vacuole Organization Piecemeal Microautophagy Of The Nucleus Phagophore Assembly Site Autophagy Autophagy Of Mitochondrion Positive Regulation Of Autophagy Regulation Of Autophagy Microautophagy Macroautophagy Positive Regulation Of Catabolic Process Intracellular Protein Localization Mitophagy Organelle Organization Cellular Component Assembly Cytoplasm Organelle Assembly Protein Modification Process Cytosol Positive Regulation Of Metabolic Process Catabolic Process Cytoplasmic Vesicle Atg1/ULK1 Kinase Complex M Band Regulation Of Macroautophagy Positive Regulation Of Macroautophagy Protein Phosphorylation Protein-phosphatidylethanolamide Deconjugating Activity Establishment Of Protein Localization Protein Serine Kinase Activity Regulation Of Signal Transduction Protein Transport Regulation Of Cell Communication Protein Delipidation Phosphorylation Protein Serine/threonine Kinase Activity Protein Kinase Activity Protein Metabolic Process Regulation Of Signaling Regulation Of Intracellular Signal Transduction Phagophore Assembly Site Membrane Protein Localization To Organelle Defense Response Negative Regulation Of Cell Communication Negative Regulation Of Signaling Cell Junction Organization Response To Starvation	Mitophagy Autophagy Of Mitochondrion Autophagosome Organization Autophagosome Assembly Protein Kinase Regulator Activity Macroautophagy Piecemeal Microautophagy Of The Nucleus Vacuole Organization Microautophagy Nucleophagy Autophagy Tissue Morphogenesis Neural Plate Axis Specification Autophagosome Epithelial Tube Morphogenesis Myosin II Heavy Chain Binding Response To Chlorate Negative Regulation Of Cell Population Proliferation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Muscle Tissue Development Intracellular Protein Localization Epidermal Cell Fate Specification Smoothened Binding Hedgehog Family Protein Binding Hedgehog Receptor Activity Organelle Assembly Positive Regulation Of Protein K48-linked Ubiquitination Protein-phosphatidylethanolamide Deconjugating Activity Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Processing Release From Viral Latency Protein Delipidation Positive Regulation Of Activin Receptor Signaling Pathway Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Viral Life Cycle Response To Mitochondrial Depolarisation Regulation Of Protein K48-linked Ubiquitination Adiponectin-activated Signaling Pathway Patched Binding Cell Proliferation Involved In Metanephros Development Mammary Gland Duct Morphogenesis Neural Tube Patterning Dendritic Growth Cone Regulation Of Protein Localization Atg1/ULK1 Kinase Complex Neural Tube Formation Metanephric Collecting Duct Development Cell Proliferation Involved In Kidney Development
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