VPS26C and IFNL1

		VPS26C	IFNL1
Description		VPS26 endosomal protein sorting factor C	interferon lambda 1
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GO Annotations	Cellular Component	Nucleus Endosome	Extracellular Region Extracellular Space Interleukin-28 Receptor Complex
	Molecular Function	Protein Binding	Signaling Receptor Binding Cytokine Activity Interleukin-28 Receptor Binding
	Biological Process	Intracellular Protein Transport Endocytic Recycling	Negative Regulation Of Type 2 Immune Response Cell Surface Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Cell Population Proliferation Negative Regulation Of Interleukin-13 Production Negative Regulation Of Interleukin-5 Production Positive Regulation Of Type II Interferon Production Type III Interferon-mediated Signaling Pathway Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Negative Regulation Of Memory T Cell Differentiation Innate Immune Response Positive Regulation Of MHC Class I Biosynthetic Process Negative Regulation Of T Cell Differentiation Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Immune Response Defense Response To Virus Cellular Response To Virus
Pathways			Other interleukin signaling Interleukin-20 family signaling
Drugs
Diseases
GWAS
Interacting Genes		56 interacting genes: AGTPBP1 ARHGAP21 ARHGEF12 ASH1L CA14 CBLB CCDC85A CD55 CIPC DCLK1 DDIT4L DECR2 DNAJB2 DOP1B DSCR4 DSCR8 EPHB6 IFNL1 INCA1 KIF1A KIF21A LRIF1 MAML3 MAPK6 MAPK8IP1 MDM4 MEI4 MEOX2 MRPS35 MSTO1 MYRIP NRCAM NSMF PALS2 PCM1 PEG10 PIGP PMS2 POU3F4 PRKD2 PTPN21 RAB39B RAP1GAP RAP1GAP2 RIGI SETMAR SYNJ1 TAF1C TEPSIN TET2 TRAPPC1 U2AF1 VPS26A VPS35L XPA ZNF655	2 interacting genes: IFNLR1 VPS26C
Entrez ID		10311	282618
HPRD ID		10390	09588
Ensembl ID		ENSG00000157538	ENSG00000182393
Uniprot IDs		A8MTY9 A8MY26 O14972	A0A7R8C391 Q8IU54
PDB IDs		8P0X 8SYN 8SYO 9AU7	3OG4 3OG6
Enriched GO Terms of Interacting Partners?			Interleukin-28 Receptor Complex Response To Type III Interferon Type III Interferon-mediated Signaling Pathway Positive Regulation Of Cellular Respiration Mucosal Immune Response Cytokine Receptor Activity Regulation Of Defense Response To Virus By Host Regulation Of Cellular Respiration Organ Or Tissue Specific Immune Response Endocytic Recycling Cellular Response To Virus Regulation Of Defense Response To Virus Interferon-mediated Signaling Pathway
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