RUSC2 and SIGMAR1

		RUSC2	SIGMAR1
Description		RUN and SH3 domain containing 2	sigma non-opioid intracellular receptor 1
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GO Annotations	Cellular Component	Cytosol Cytoplasmic Vesicle Extracellular Exosome	Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Cytosol Postsynaptic Density Membrane Integral Component Of Membrane Growth Cone Cytoplasmic Vesicle Postsynaptic Density Membrane
	Molecular Function	Protein Binding Small GTPase Binding	G Protein-coupled Opioid Receptor Activity Protein Binding
	Biological Process	Biological_process	Lipid Transport Nervous System Development Cell Death In Response To Hydrogen Peroxide G Protein-coupled Opioid Receptor Signaling Pathway Regulation Of Neuron Apoptotic Process Protein Homotrimerization
Pathways			Potential therapeutics for SARS
Drugs			Amitriptyline Remoxipride Haloperidol Dextromethorphan Nortriptyline Fenfluramine Pentazocine Cocaine Hydrocodone Sertraline Dimethyltryptamine Prasterone Phencyclidine Noscapine Captodiame Pentoxyverine
Diseases
GWAS		Psoriasis ( 25903422)
Interacting Genes		11 interacting genes: DLST EGFR FXR1 GIT2 GOLGA2 KHDRBS1 MAGEC1 RAB1A RAB1B SIGMAR1 SRPRA	14 interacting genes: ANK2 DCAF12 DNAJB5 GHSR GNE ITPR3 NFX1 PDZD11 PHF24 RECK RUSC2 SPAG8 SPINK4 VCP
Entrez ID		9853	10280
HPRD ID		18009	03580
Ensembl ID		ENSG00000198853	ENSG00000147955
Uniprot IDs		Q8N2Y8	A2A3U5 B4DR71 Q99720
PDB IDs		6IF2	5HK1 5HK2 6DJZ 6DK0 6DK1
Enriched GO Terms of Interacting Partners?
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