SH3BP5 and TNKS

  • Number of citations of the paper that reports this interaction (PubMedID 17043677)
  • 193
  • Data Source:
  • BioGRID (two hybrid)

SH3BP5

TNKS

Description SH3 domain binding protein 5 tankyrase
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acne (severe) ( 24927181)
  • Age at first birth ( 34211149)
  • Alanine aminotransferase levels ( 33547301 34315874)
  • Aspartate aminotransferase levels ( 34315874)
  • Bipolar disorder ( 31043756)
  • Body shape index ( 34021172)
  • Bone mineral density (Ward's triangle area) ( 27397699)
  • Brain morphology (MOSTest) ( 32665545)
  • Cataracts (operation) ( 31816047)
  • Deep white matter hyperintensities ( 32517579)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Fish- and plant-related diet ( 32066663)
  • General risk tolerance (MTAG) ( 30643258)
  • Joint mobility (Beighton score) ( 27182965)
  • LDL cholesterol levels ( 32203549)
  • Metabolite levels ( 22916037)
  • Mosquito bite size ( 28199695)
  • Nose size ( 27182965)
  • Obesity (early onset extreme) ( 20421936)
  • Oily fish consumption ( 32066663)
  • Pork consumption ( 32066663)
  • Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Refractive error ( 32231278)
  • Regular attendance at a religious group ( 29970889)
  • Response to inhaled corticosteroid treatment in asthma (change in FEV1) ( 24792382)
  • Response to radiotherapy in nasopharyngeal carcinoma (acute oral mucositis) ( 32503578)
  • Schizophrenia ( 26198764)
  • Serum alkaline phosphatase levels ( 33547301)
  • Systemic lupus erythematosus ( 28714469)
  • Systolic blood pressure ( 30224653)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Triglyceride levels ( 32154731)
  • Type 2 diabetes ( 30054458)
  • Waist circumference adjusted for body mass index ( 34021172)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
  • White matter hyperintensity volume ( 33293549)
  • White matter hyperintensity volume (adjusted for hypertension) ( 33293549)
  • White matter hyperintensity volume x hypertension interaction (2df) ( 33293549)
Interacting Genes 16 interacting genes: APP BTK CDC5L DISC1 DST EXOC1 IFT20 MAPK10 MAPK12 MAPK8 MAPK9 NAP1L2 SOS1 SPTBN1 SYNE1 TNKS 25 interacting genes: ADPRS ANKRD28 BABAM1 DISC1 EIF4A1 EPM2AIP1 FANCD2 FNBP1 LNPEP MCL1 NELFE NUMA1 OARD1 POT1 PTEN SDCBP SH3BP5 TCL1A TERF1 TNIK TNKS1BP1 TNKS2 UBASH3B USP25 VPS33A
Entrez ID 9467 8658
HPRD ID 12030 04490
Ensembl ID ENSG00000131370 ENSG00000173273
Uniprot IDs A0A024R2J3 O60239 O95271
PDB IDs 4H3B 6DJL 6IXE 6IXF 6IXG 6IXV 2RF5 3UDD 3UH2 3UH4 4DVI 4I9I 4K4E 4K4F 4KRS 4LI6 4LI7 4LI8 4MSG 4MSK 4MT9 4N3R 4N4V 4OA7 4TOR 4TOS 4U6A 4UUH 4UW1 4W5S 4W6E 5EBT 5ECE 5ETY 5GP7 5JHQ 5JTI 5JU5 5KNI 6QXU 6URQ
Enriched GO Terms of Interacting Partners?
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