TNKS and ANKRD28

  • Number of citations of the paper that reports this interaction (PubMedID 23414517)
  • 13
  • Data Source:
  • BioGRID (two hybrid)

TNKS

ANKRD28

Description tankyrase ankyrin repeat domain 28
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acne (severe) ( 24927181)
  • Age at first birth ( 34211149)
  • Alanine aminotransferase levels ( 33547301 34315874)
  • Aspartate aminotransferase levels ( 34315874)
  • Bipolar disorder ( 31043756)
  • Body shape index ( 34021172)
  • Bone mineral density (Ward's triangle area) ( 27397699)
  • Brain morphology (MOSTest) ( 32665545)
  • Cataracts (operation) ( 31816047)
  • Deep white matter hyperintensities ( 32517579)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Fish- and plant-related diet ( 32066663)
  • General risk tolerance (MTAG) ( 30643258)
  • Joint mobility (Beighton score) ( 27182965)
  • LDL cholesterol levels ( 32203549)
  • Metabolite levels ( 22916037)
  • Mosquito bite size ( 28199695)
  • Nose size ( 27182965)
  • Obesity (early onset extreme) ( 20421936)
  • Oily fish consumption ( 32066663)
  • Pork consumption ( 32066663)
  • Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Refractive error ( 32231278)
  • Regular attendance at a religious group ( 29970889)
  • Response to inhaled corticosteroid treatment in asthma (change in FEV1) ( 24792382)
  • Response to radiotherapy in nasopharyngeal carcinoma (acute oral mucositis) ( 32503578)
  • Schizophrenia ( 26198764)
  • Serum alkaline phosphatase levels ( 33547301)
  • Systemic lupus erythematosus ( 28714469)
  • Systolic blood pressure ( 30224653)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858)
  • Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
  • Triglyceride levels ( 32154731)
  • Type 2 diabetes ( 30054458)
  • Waist circumference adjusted for body mass index ( 34021172)
  • Waist-hip index ( 34021172)
  • Waist-to-hip ratio adjusted for BMI ( 34021172)
  • White matter hyperintensity volume ( 33293549)
  • White matter hyperintensity volume (adjusted for hypertension) ( 33293549)
  • White matter hyperintensity volume x hypertension interaction (2df) ( 33293549)
Interacting Genes 25 interacting genes: ADPRS ANKRD28 BABAM1 DISC1 EIF4A1 EPM2AIP1 FANCD2 FNBP1 LNPEP MCL1 NELFE NUMA1 OARD1 POT1 PTEN SDCBP SH3BP5 TCL1A TERF1 TNIK TNKS1BP1 TNKS2 UBASH3B USP25 VPS33A 34 interacting genes: ABCF2 AGPAT2 ANK2 ANKRD26 ANKRD50 BCL3 BRCA1 CCDC187 CD164 CSNK2B EEF1G EHMT2 EIF3D GADD45GIP1 HNRNPK HNRNPR INCA1 KCNV2 MYOM1 NOTCH2 NOTCH3 PIBF1 PTRH1 RNF11 TGM2 TGS1 THAP7 TMIE TNKS TNKS2 TTN UACA YTHDC1 ZNF512B
Entrez ID 8658 23243
HPRD ID 04490 10651
Ensembl ID ENSG00000173273 ENSG00000206560
Uniprot IDs O95271 A0A024R2I9 O15084
PDB IDs 2RF5 3UDD 3UH2 3UH4 4DVI 4I9I 4K4E 4K4F 4KRS 4LI6 4LI7 4LI8 4MSG 4MSK 4MT9 4N3R 4N4V 4OA7 4TOR 4TOS 4U6A 4UUH 4UW1 4W5S 4W6E 5EBT 5ECE 5ETY 5GP7 5JHQ 5JTI 5JU5 5KNI 6QXU 6URQ
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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