CD2 and LGALS1

Number of citations of the paper that reports this interaction (PubMedID 10642604)
15

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		CD2	LGALS1
Description		CD2 molecule	galectin 1
Image
GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction External Side Of Plasma Membrane Cytoplasmic Side Of Plasma Membrane Cell Surface Protein-containing Complex Membrane Raft Anchored Component Of Plasma Membrane	Extracellular Region Extracellular Space Nucleus Cytoplasm Endoplasmic Reticulum Lumen Cytosol Cell Surface Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Signaling Receptor Binding Protein Binding Receptor Tyrosine Kinase Binding Signaling Receptor Activity Identical Protein Binding Protein Self-association	RNA Binding Protein Binding Carbohydrate Binding Lactose Binding Identical Protein Binding Laminin Binding
	Biological Process	Membrane Raft Polarization Apoptotic Process Cell Surface Receptor Signaling Pathway Natural Killer Cell Activation Positive Regulation Of Myeloid Dendritic Cell Activation Positive Regulation Of Interferon-gamma Production Positive Regulation Of Interleukin-8 Production Positive Regulation Of Tumor Necrosis Factor Production Heterotypic Cell-cell Adhesion T Cell Activation Regulation Of T Cell Differentiation Cell-cell Adhesion	Plasma Cell Differentiation Apoptotic Process Response To Xenobiotic Stimulus Negative Regulation Of Cell-substrate Adhesion Negative Regulation Of Neuron Projection Development T Cell Costimulation Positive Regulation Of Erythrocyte Aggregation Response To Isolation Stress Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Myoblast Differentiation Positive Regulation Of Viral Entry Into Host Cell Response To Axon Injury Cellular Response To Glucose Stimulus Cellular Response To Organic Cyclic Compound Positive Regulation Of Dendritic Cell Differentiation
Pathways		Cell surface interactions at the vascular wall	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs		Alefacept Siplizumab	Mercaptoethanol Thiodigalactoside 1,4-Dithiothreitol Artenimol
Diseases
GWAS		Body mass index ( 28552196) Gout (normal type) ( 32238385) Medication use (thyroid preparations) ( 31015401) Multiple sclerosis ( 31604244) Rheumatoid arthritis ( 30423114 24390342) Rheumatoid arthritis (ACPA-positive) ( 23143596 24532676)	Fat distribution (HIV) ( 21897333)
Interacting Genes		23 interacting genes: CD247 CD2AP CD2BP2 CD4 CD48 CD5 CD53 CD58 CD59 DNAJC5 FYN LCK LGALS1 LINC00311 LYAR MXD1 PSTPIP1 PTPRC RBM15 RHOC SH3KBP1 SP1 UBC	17 interacting genes: CD2 CD4 CD7 CD8A CDC42 GEMIN4 HRAS HSPB2 ITGB1 LGALS3BP MUC16 NLGN3 PTEN PTPRC SPN USP4 VPREB1
Entrez ID		914	3956
HPRD ID		01750	01040
Ensembl ID		ENSG00000116824	ENSG00000100097
Uniprot IDs		P06729 Q53F96	A0A384MR27 P09382
PDB IDs		1CDB 1GYA 1HNF 1L2Z 1QA9 2J6O 2J7I	1GZW 1W6M 1W6N 1W6O 1W6P 1W6Q 2KM2 2ZKN 3OY8 3OYW 3T2T 3W58 3W59 4Q1P 4Q1R 4Q26 4Q27 4Q2F 4XBL 4Y1U 4Y1V 4Y1X 4Y1Y 4Y1Z 4Y20 4Y22 4Y24 5MWT 5MWX 6B94 6F83
Enriched GO Terms of Interacting Partners?
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