LGALS1 and SPN

Number of citations of the paper that reports this interaction (PubMedID 10490978)
77

Data Source:
HPRD (in vivo, in vitro)

		LGALS1	SPN
Description		galectin 1	sialophorin
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytoplasm Endoplasmic Reticulum Lumen Cytosol Cell Surface Collagen-containing Extracellular Matrix Extracellular Exosome	Uropod Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Microvillus External Side Of Plasma Membrane Cell Surface Membrane PML Body Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding Carbohydrate Binding Lactose Binding Identical Protein Binding Laminin Binding	Transmembrane Signaling Receptor Activity Protein Binding Hsp70 Protein Binding Heat Shock Protein Binding
	Biological Process	Plasma Cell Differentiation Apoptotic Process Response To Xenobiotic Stimulus Negative Regulation Of Cell-substrate Adhesion Negative Regulation Of Neuron Projection Development T Cell Costimulation Positive Regulation Of Erythrocyte Aggregation Response To Isolation Stress Regulation Of Apoptotic Process Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Myoblast Differentiation Positive Regulation Of Viral Entry Into Host Cell Response To Axon Injury Cellular Response To Glucose Stimulus Cellular Response To Organic Cyclic Compound Positive Regulation Of Dendritic Cell Differentiation	T-helper 1 Cell Lineage Commitment Chemotaxis Immune Response Cellular Defense Response Negative Regulation Of Cell Adhesion Establishment Or Maintenance Of Cell Polarity Signal Transduction Cell Surface Receptor Signaling Pathway Positive Regulation Of Tumor Necrosis Factor Production Negative Regulation Of T Cell Proliferation Defense Response To Bacterium Regulation Of Immune Response Leukocyte Tethering Or Rolling Regulation Of T Cell Migration Positive Regulation Of T Cell Migration
Pathways		Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation	Cell surface interactions at the vascular wall Basigin interactions
Drugs		Mercaptoethanol Thiodigalactoside 1,4-Dithiothreitol Artenimol
Diseases
GWAS		Fat distribution (HIV) ( 21897333)
Interacting Genes		17 interacting genes: CD2 CD4 CD7 CD8A CDC42 GEMIN4 HRAS HSPB2 ITGB1 LGALS3BP MUC16 NLGN3 PTEN PTPRC SPN USP4 VPREB1	18 interacting genes: ARL13B CLCA4 CTNNB1 CTSA CXCL16 CYBC1 DAXX ERGIC3 EZR FYN ICAM1 LGALS1 LMNA MSN PLP2 SGTA SIGLEC1 UBQLN2
Entrez ID		3956	6693
HPRD ID		01040	06770
Ensembl ID		ENSG00000100097	ENSG00000197471
Uniprot IDs		A0A384MR27 P09382	A0A024R629 P16150
PDB IDs		1GZW 1W6M 1W6N 1W6O 1W6P 1W6Q 2KM2 2ZKN 3OY8 3OYW 3T2T 3W58 3W59 4Q1P 4Q1R 4Q26 4Q27 4Q2F 4XBL 4Y1U 4Y1V 4Y1X 4Y1Y 4Y1Z 4Y20 4Y22 4Y24 5MWT 5MWX 6B94 6F83
Enriched GO Terms of Interacting Partners?
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