PRPF18 and HOMEZ

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PRPF18	HOMEZ
Description		pre-mRNA processing factor 18	homeobox and leucine zipper encoding
Image
GO Annotations	Cellular Component	Nucleus Spliceosomal Complex U5 SnRNP Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U2-type Post-spliceosomal Complex	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function	Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding
	Biological Process	Generation Of Catalytic Spliceosome For Second Transesterification Step MRNA Processing RNA Splicing Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+epirubicin+/-5FU) ( 24025145) Craniofacial microsomia ( 26853712) Lupus nephritis in systemic lupus erythematosus ( 24925725) Post bronchodilator FEV1/FVC ratio ( 26634245) Skin pigmentation ( 28300201)	Height ( 31562340) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 34021172) Mean platelet volume ( 32888494) Pulse pressure ( 27841878) Reticulocyte count ( 32888494) Serum alkaline phosphatase levels ( 33547301) Systolic blood pressure ( 27841878)
Interacting Genes		81 interacting genes: AGTRAP AMOTL2 AP2M1 ASCC2 BEGAIN BICD2 BLZF1 CADPS CALCOCO2 CARD10 CARD9 CBY2 CCDC102B CCDC136 CCDC150 CCDC57 CCNC CDR2 CEP70 CSRNP1 DVL3 EFHC2 EVI5L FERMT3 FSD2 GAS8 GCC1 GOLGA2 GOLGA6L9 GPBP1 GRIPAP1 HMBOX1 HOMEZ HOOK2 HSF2BP IKBKG IKZF1 KANK2 KCTD7 KIFC3 KRT31 KRT34 KRT35 KRT39 KRT40 LDOC1 LZTS1 LZTS2 MCC MDFI MEOX2 MTUS2 NACC1 NECAB2 NINL NUTM1 NUTM2F OSBPL3 PDE9A PFDN5 PIBF1 PICK1 PLEKHG4 PNMA1 PPIH PRKAR1B RHOU RINT1 SCHIP1 SPRED1 STX11 TRAF2 TRIM23 TRIM27 TRIM54 TSNAX TSNAXIP1 UBXN11 ZNF526 ZNF639 ZRANB1	114 interacting genes: ACTR10 AEN ANKRD11 ANKRD2 ARHGAP9 ASB6 AXIN1 BIVM BYSL C2orf42 CBX8 CCDC13 CCDC187 CCHCR1 CCNK CDC7 CENPS CENPS-CORT CFAP206 CTNNA3 DEF6 DGCR6 DHX16 DNTTIP1 EBF1 EIF4E2 ELOA ENKD1 FAM90A1 FARS2 GAS8 GFAP GPANK1 GRB2 HOXC8 HSF2BP IL16 INO80B JAKMIP2 KIFC3 KPNA2 LENG1 LGALS4 LMO1 LMO3 LNX1 LRRC7 LSM4 MAD2L1BP MAFG MAPK1 MED18 MORF4L2 MOS MRPL11 NCK1 NCK2 NEIL2 NEK6 NXF1 OSGIN1 PARVG PHF1 PHF19 PIBF1 PIN1 PLEKHA7 POLDIP3 PRKAA1 PRKAA2 PRPF18 PSMA1 RASL10A RBM39 RNF8 RPGR RPL9 RPP25 RPS25 SCNM1 SDCBP SEC23A SH3RF2 SMARCB1 SMARCD1 SMYD1 SNRPB2 SUMO2 SUMO3 TARS2 TBC1D30 TCEA2 TCEANC TEAD4 TLE5 TRAF4 TSGA10IP TXK USF1 VEZF1 VPS9D1 ZBTB25 ZBTB7A ZMYND19 ZNF165 ZNF250 ZNF280C ZNF35 ZNF417 ZNF580 ZNF629 ZNF688 ZNF76 ZSCAN5B
Entrez ID		8559	57594
HPRD ID		05407	12167
Ensembl ID		ENSG00000165630	ENSG00000215271
Uniprot IDs		Q99633	Q8IX15
PDB IDs		2DK4	2ECC 2YS9
Enriched GO Terms of Interacting Partners?
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