HOMEZ and CENPS

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid)

		HOMEZ	CENPS
Description		homeobox and leucine zipper encoding	centromere protein S
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus Cytosol	Kinetochore Nucleoplasm Cytosol Fanconi Anaemia Nuclear Complex FANCM-MHF Complex
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding	DNA Binding Chromatin Binding Double-stranded DNA Binding Protein Binding Protein Heterodimerization Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Resolution Of Meiotic Recombination Intermediates DNA Repair Cellular Response To DNA Damage Stimulus Replication Fork Processing Positive Regulation Of Protein Ubiquitination Cell Division Kinetochore Assembly
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Fanconi Anemia Pathway Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Height ( 31562340) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 34021172) Mean platelet volume ( 32888494) Pulse pressure ( 27841878) Reticulocyte count ( 32888494) Serum alkaline phosphatase levels ( 33547301) Systolic blood pressure ( 27841878)
Interacting Genes		114 interacting genes: ACTR10 AEN ANKRD11 ANKRD2 ARHGAP9 ASB6 AXIN1 BIVM BYSL C2orf42 CBX8 CCDC13 CCDC187 CCHCR1 CCNK CDC7 CENPS CENPS-CORT CFAP206 CTNNA3 DEF6 DGCR6 DHX16 DNTTIP1 EBF1 EIF4E2 ELOA ENKD1 FAM90A1 FARS2 GAS8 GFAP GPANK1 GRB2 HOXC8 HSF2BP IL16 INO80B JAKMIP2 KIFC3 KPNA2 LENG1 LGALS4 LMO1 LMO3 LNX1 LRRC7 LSM4 MAD2L1BP MAFG MAPK1 MED18 MORF4L2 MOS MRPL11 NCK1 NCK2 NEIL2 NEK6 NXF1 OSGIN1 PARVG PHF1 PHF19 PIBF1 PIN1 PLEKHA7 POLDIP3 PRKAA1 PRKAA2 PRPF18 PSMA1 RASL10A RBM39 RNF8 RPGR RPL9 RPP25 RPS25 SCNM1 SDCBP SEC23A SH3RF2 SMARCB1 SMARCD1 SMYD1 SNRPB2 SUMO2 SUMO3 TARS2 TBC1D30 TCEA2 TCEANC TEAD4 TLE5 TRAF4 TSGA10IP TXK USF1 VEZF1 VPS9D1 ZBTB25 ZBTB7A ZMYND19 ZNF165 ZNF250 ZNF280C ZNF35 ZNF417 ZNF580 ZNF629 ZNF688 ZNF76 ZSCAN5B	4 interacting genes: APP CENPM CENPX HOMEZ
Entrez ID		57594	378708
HPRD ID		12167	18797
Ensembl ID		ENSG00000215271	ENSG00000175279
Uniprot IDs		Q8IX15	Q8N2Z9
PDB IDs		2ECC 2YS9	4DRA 4DRB 4E44 4E45 4NDY 4NE1 4NE3 4NE5 4NE6
Enriched GO Terms of Interacting Partners?
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