GAS7 and CREB3L2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		GAS7	CREB3L2
Description		growth arrest specific 7	cAMP responsive element binding protein 3 like 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Actin Filament Plasma Membrane	Chromatin Nucleus Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Perinuclear Endoplasmic Reticulum
	Molecular Function	Protein Binding Actin Filament Binding	Transcription Cis-regulatory Region Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific CAMP Response Element Binding
	Biological Process	Actin Filament Polymerization Neuron Projection Morphogenesis	Chondrocyte Differentiation Regulation Of Transcription By RNA Polymerase II Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Response To Wounding Positive Regulation Of Gene Expression Positive Regulation Of Neuron Projection Development Endoplasmic Reticulum Unfolded Protein Response Response To Endoplasmic Reticulum Stress Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Cartilage Development
Pathways			CREB3 factors activate genes
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Declining hemoglobin trajectory in blood donors ( 33491795) Glaucoma ( 30104761 31959993 30054594) Glaucoma (high intraocular pressure) ( 33627673) Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary open-angle) ( 33627673 29891935) Gut microbiota relative abundance (Prevotella) ( 33208821) Heel bone mineral density ( 30598549) Intraocular pressure ( 29617998 25173106 24002674 22570627 31798171 29785010 31959993 30054594 28073927 29235454) Medication use (antiglaucoma preparations and miotics) ( 31015401) Proteinuria and chronic kidney disease ( 26420894)	Body fat distribution (trunk fat ratio) ( 30664634) Body shape index ( 34021172) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Liver enzyme levels (alkaline phosphatase) ( 33972514) Metabolite levels ( 23823483) Monocyte count ( 32888494) Pulse pressure ( 27841878) Refractive error ( 32231278) Total cholesterol levels ( 31217584) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		26 interacting genes: ABI1 ACTA1 APBB1IP ATXN1L CDC37 CREB3L2 CYFIP1 CYFIP2 DIAPH1 FMNL1 GAPDH KHDRBS1 LSM4 MCRS1 MYBPC2 NCKAP1 NCKAP1L NCKIPSD NTAQ1 PACSIN1 RPLP0 SF1 SF3A1 SFPQ WASF2 YIF1A	10 interacting genes: CEP19 GABARAPL1 GAS7 GCFC2 GULP1 PTP4A1 PXN RGS16 RND1 ZNF212
Entrez ID		8522	64764
HPRD ID		16011	16391
Ensembl ID		ENSG00000007237	ENSG00000182158
Uniprot IDs		O60861	Q68D60 Q70SY1
PDB IDs		2LX7 2YSH
Enriched GO Terms of Interacting Partners?
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