GAS7 and APBB1IP

Number of citations of the paper that reports this interaction (PubMedID 16055720)
92

Data Source:
BioGRID (pull down)

		GAS7	APBB1IP
Description		growth arrest specific 7	amyloid beta precursor protein binding family B member 1 interacting protein
Image
GO Annotations	Cellular Component	Cytoplasm Actin Filament Plasma Membrane	Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Lamellipodium T Cell Receptor Complex
	Molecular Function	Protein Binding Actin Filament Binding	Protein Binding
	Biological Process	Actin Filament Polymerization Neuron Projection Morphogenesis	T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell Signal Transduction Positive Regulation Of Cell Adhesion
Pathways			Integrin signaling GRB2:SOS provides linkage to MAPK signaling for Integrins p130Cas linkage to MAPK signaling for integrins MAP2K and MAPK activation Signaling by moderate kinase activity BRAF mutants Signaling by high-kinase activity BRAF mutants Signaling by BRAF and RAF1 fusions Paradoxical activation of RAF signaling by kinase inactive BRAF Signaling downstream of RAS mutants Signaling by RAF1 mutants
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Declining hemoglobin trajectory in blood donors ( 33491795) Glaucoma ( 30104761 31959993 30054594) Glaucoma (high intraocular pressure) ( 33627673) Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary open-angle) ( 33627673 29891935) Gut microbiota relative abundance (Prevotella) ( 33208821) Heel bone mineral density ( 30598549) Intraocular pressure ( 29617998 25173106 24002674 22570627 31798171 29785010 31959993 30054594 28073927 29235454) Medication use (antiglaucoma preparations and miotics) ( 31015401) Proteinuria and chronic kidney disease ( 26420894)	Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Eosinophil counts ( 32888494 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 32888494 27863252) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494 27863252) Inflammatory biomarkers ( 22228203) Lymphocyte counts ( 32888494) Monocyte percentage of white cells ( 32888494 27863252) Neutrophil percentage of granulocytes ( 27863252) Response to angiotensin II receptor blocker therapy ( 22566498) Sum eosinophil basophil counts ( 27863252) White blood cell count ( 32888494) White blood cell count (basophil) ( 27863252)
Interacting Genes		26 interacting genes: ABI1 ACTA1 APBB1IP ATXN1L CDC37 CREB3L2 CYFIP1 CYFIP2 DIAPH1 FMNL1 GAPDH KHDRBS1 LSM4 MCRS1 MYBPC2 NCKAP1 NCKAP1L NCKIPSD NTAQ1 PACSIN1 RPLP0 SF1 SF3A1 SFPQ WASF2 YIF1A	13 interacting genes: BAG6 EVL GAS7 GPR158 HRAS NDN PFN1 PRPF40A RAB18 RAP1A TLX3 VASP ZDHHC17
Entrez ID		8522	54518
HPRD ID		16011	16420
Ensembl ID		ENSG00000007237	ENSG00000077420
Uniprot IDs		O60861	Q7Z5R6
PDB IDs		2LX7 2YSH	2MWN 3ZDL
Enriched GO Terms of Interacting Partners?
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