CREB3L2 and RGS16

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		CREB3L2	RGS16
Description		cAMP responsive element binding protein 3 like 2	regulator of G protein signaling 16
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Perinuclear Endoplasmic Reticulum	Cytoplasm Plasma Membrane Intrinsic Component Of Membrane
	Molecular Function	Transcription Cis-regulatory Region Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific CAMP Response Element Binding	GTPase Activity GTPase Activator Activity Protein Binding Calmodulin Binding
	Biological Process	Chondrocyte Differentiation Regulation Of Transcription By RNA Polymerase II Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Response To Wounding Positive Regulation Of Gene Expression Positive Regulation Of Neuron Projection Development Endoplasmic Reticulum Unfolded Protein Response Response To Endoplasmic Reticulum Stress Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Cartilage Development	G Protein-coupled Receptor Signaling Pathway Visual Perception Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Signal Transduction Positive Regulation Of GTPase Activity
Pathways		CREB3 factors activate genes	G alpha (q) signalling events G alpha (i) signalling events G alpha (i) signalling events G alpha (z) signalling events
Drugs
Diseases
GWAS		Body fat distribution (trunk fat ratio) ( 30664634) Body shape index ( 34021172) Height ( 31562340) Hip circumference adjusted for BMI ( 34021172) LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Liver enzyme levels (alkaline phosphatase) ( 33972514) Metabolite levels ( 23823483) Monocyte count ( 32888494) Pulse pressure ( 27841878) Refractive error ( 32231278) Total cholesterol levels ( 31217584) Waist circumference adjusted for body mass index ( 34021172)	Chronotype ( 26955885 30696823 27494321) Morning person ( 30696823) Morning vs. evening chronotype ( 26955885 26835600 27494321) Sleep traits (multi-trait analysis) ( 27992416)
Interacting Genes		10 interacting genes: CEP19 GABARAPL1 GAS7 GCFC2 GULP1 PTP4A1 PXN RGS16 RND1 ZNF212	14 interacting genes: CREB3L2 CSK EGFR GDE1 GNA13 GNAI1 GNAI2 GNAI3 GNAO1 GNAQ GNAT1 LYN SRC ST14
Entrez ID		64764	6004
HPRD ID		16391	03945
Ensembl ID		ENSG00000182158	ENSG00000143333
Uniprot IDs		Q68D60 Q70SY1	O15492
PDB IDs			2BT2 2IK8
Enriched GO Terms of Interacting Partners?
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