ITCH and ARID1A

  • Number of citations of the paper that reports this interaction (PubMedID 16055720)
  • 92

ITCH

ARID1A

Description itchy E3 ubiquitin protein ligase AT-rich interaction domain 1A
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alanine aminotransferase levels ( 33547301)
  • Apolipoprotein A1 levels ( 32203549)
  • Apolipoprotein B levels ( 32203549)
  • Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143)
  • Granulocyte percentage of myeloid white cells ( 27863252)
  • HDL cholesterol levels ( 32203549 30698716)
  • HDL cholesterol levels in current drinkers ( 30698716)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Heel bone mineral density ( 30598549 28869591)
  • LDL cholesterol levels ( 32203549)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Liver volume ( 34128465)
  • Metabolic syndrome ( 31589552)
  • Monocyte percentage of white cells ( 27863252)
  • Neutrophil count ( 32888494)
  • Platelet count ( 32888494)
  • Plateletcrit ( 32888494)
  • Rosacea symptom severity ( 29771307)
  • Total cholesterol levels ( 33339817)
  • Triglyceride levels ( 32203549)
  • Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • White matter hyperintensities in ischemic stroke ( 26674333)
Interacting Genes 108 interacting genes: AGO2 ARHGEF7 ARID1A ARRB2 ARRDC3 ATN1 BECN1 BIN1 BRAF CBL CBLC CDC34 CEP250 CPSF6 CPSF7 CSNK2A1 CXCR4 CYLD DAZAP1 DTX1 DTX3L ERBB4 EWSR1 FYN GLIS3 GNAI2 HNRNPL HNRNPUL1 JUN JUNB KPNB1 KSR1 LAPTM5 LITAF LRRK1 MAP2K1 MAP2K4 MAPK8 MLANA N4BP1 NDFIP1 NDFIP2 NEDD9 NFE2 NOTCH1 NRAS NUDT21 NUMB PABPC1 PACSIN1 POLR2A POLR2B POLR2C POLR2E POU5F1 PRKACA PRRG4 RAF1 RIPK1 RNF11 RPAP2 RPAP3 SCNN1A SCNN1B SF1 SGK3 SH3GL1 SH3GL2 SMAD2 SMAD3 SMARCC1 SMARCC2 SMARCE1 SMN1 SNX9 SPART STAM2 SUFU TAB1 TP63 TP73 TRPC4 TRPV1 TRPV4 UBAP2 UBAP2L UBC UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2G1 UBE2J2 UBE2K UBE2L3 UBE2M UBE2O UBE2Q1 UBE2Q2 UBE2R2 URI1 WASL WBP2 YWHAQ 24 interacting genes: CDC123 EDEM1 ESR1 EWSR1 FUS GATA1 GMEB1 HIC1 ITCH KLF1 MLLT1 NCOA1 NEDD4 PGR RARA RARB RARG SMARCA4 SMPDL3B TAF12 TAF15 THEMIS2 TP53 VPS41
Entrez ID 83737 8289
HPRD ID 07565 04319
Ensembl ID ENSG00000078747 ENSG00000117713
Uniprot IDs A0A590UJQ1 Q96J02 O14497
PDB IDs 2DMV 2KYK 2NQ3 2P4R 2YSF 3TUG 4ROF 5C7M 5CQ2 5DWS 5DZD 5SXP 1RYU 6LTH 6LTJ
Enriched GO Terms of Interacting Partners?
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