ITCH and AGO2

  • Number of citations of the paper that reports this interaction (PubMedID 32392088)
  • 22
  • Data Source:
  • BioGRID (unspecified method)

ITCH

AGO2

Description itchy E3 ubiquitin protein ligase argonaute RISC catalytic component 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
  • Mean corpuscular hemoglobin ( 32888494)
  • Mean corpuscular volume ( 32888494)
  • Mean reticulocyte volume ( 32888494)
  • Mean spheric corpuscular volume ( 32888494)
  • Multisite chronic pain ( 33830993)
  • Neurociticism ( 29500382)
  • Type 1 diabetes ( 34012112)
Interacting Genes 108 interacting genes: AGO2 ARHGEF7 ARID1A ARRB2 ARRDC3 ATN1 BECN1 BIN1 BRAF CBL CBLC CDC34 CEP250 CPSF6 CPSF7 CSNK2A1 CXCR4 CYLD DAZAP1 DTX1 DTX3L ERBB4 EWSR1 FYN GLIS3 GNAI2 HNRNPL HNRNPUL1 JUN JUNB KPNB1 KSR1 LAPTM5 LITAF LRRK1 MAP2K1 MAP2K4 MAPK8 MLANA N4BP1 NDFIP1 NDFIP2 NEDD9 NFE2 NOTCH1 NRAS NUDT21 NUMB PABPC1 PACSIN1 POLR2A POLR2B POLR2C POLR2E POU5F1 PRKACA PRRG4 RAF1 RIPK1 RNF11 RPAP2 RPAP3 SCNN1A SCNN1B SF1 SGK3 SH3GL1 SH3GL2 SMAD2 SMAD3 SMARCC1 SMARCC2 SMARCE1 SMN1 SNX9 SPART STAM2 SUFU TAB1 TP63 TP73 TRPC4 TRPV1 TRPV4 UBAP2 UBAP2L UBC UBE2C UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2G1 UBE2J2 UBE2K UBE2L3 UBE2M UBE2O UBE2Q1 UBE2Q2 UBE2R2 URI1 WASL WBP2 YWHAQ 27 interacting genes: AGO1 BTRC DCP1A DCP2 DDX20 DHX58 DICER1 GEMIN4 ITCH KAT5 LINC00467 MAPKAPK2 MIR19A MIRLET7B MIRLET7I NSD2 PFKP POLA2 PRKRA RAD51 TARBP2 TBK1 TBKBP1 TRIM55 TRIM63 UBAP2L UBC
Entrez ID 83737 27161
HPRD ID 07565 06943
Ensembl ID ENSG00000078747 ENSG00000123908
Uniprot IDs A0A590UJQ1 Q96J02 Q9UKV8
PDB IDs 2DMV 2KYK 2NQ3 2P4R 2YSF 3TUG 4ROF 5C7M 5CQ2 5DWS 5DZD 5SXP 3LUC 3LUD 3LUG 3LUH 3LUJ 3LUK 3QX8 3QX9 4F3T 4OLA 4OLB 4W5N 4W5O 4W5Q 4W5R 4W5T 4Z4C 4Z4D 4Z4E 4Z4F 4Z4G 4Z4H 4Z4I 5JS1 5JS2 5KI6 5T7B 5WEA 6CBD 6MDZ 6MFN 6MFR 6N4O 6NIT 6RA4 7C6B 7D7U
Enriched GO Terms of Interacting Partners?
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