ARID1A and GMEB1

		ARID1A	GMEB1
Description		AT-rich interaction domain 1A	glucocorticoid modulatory element binding protein 1
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm SWI/SNF Complex Brahma Complex NpBAF Complex NBAF Complex	Chromatin Nucleus Nucleoplasm Cytoplasm
	Molecular Function	DNA Binding Transcription Coactivator Activity Protein Binding Nuclear Receptor Binding Nucleosome Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Metal Ion Binding Hsp27 Protein Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Nervous System Development Intracellular Estrogen Receptor Signaling Pathway Androgen Receptor Signaling Pathway Nucleosome Mobilization Glucocorticoid Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Chromatin-mediated Maintenance Of Transcription	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Apolipoprotein A1 levels ( 32203549) Apolipoprotein B levels ( 32203549) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Granulocyte percentage of myeloid white cells ( 27863252) HDL cholesterol levels ( 32203549 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Heel bone mineral density ( 30598549 28869591) LDL cholesterol levels ( 32203549) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Liver volume ( 34128465) Metabolic syndrome ( 31589552) Monocyte percentage of white cells ( 27863252) Neutrophil count ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Rosacea symptom severity ( 29771307) Total cholesterol levels ( 33339817) Triglyceride levels ( 32203549) Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) White matter hyperintensities in ischemic stroke ( 26674333)	Basophil count ( 32888494)
Interacting Genes		24 interacting genes: CDC123 EDEM1 ESR1 EWSR1 FUS GATA1 GMEB1 HIC1 ITCH KLF1 MLLT1 NCOA1 NEDD4 PGR RARA RARB RARG SMARCA4 SMPDL3B TAF12 TAF15 THEMIS2 TP53 VPS41	16 interacting genes: ARID1A ATF7IP CASP8 CASP9 CREBBP DNMT3L GMEB2 MX1 NCOA2 SMAD1 SMAD3 SNIP1 SPOP TRIM55 TRIM63 UBE2I
Entrez ID		8289	10691
HPRD ID		04319	16059
Ensembl ID		ENSG00000117713	ENSG00000162419
Uniprot IDs		O14497	B1AT47 B2RCN8 Q9Y692
PDB IDs		1RYU 6LTH 6LTJ	1OQJ
Enriched GO Terms of Interacting Partners?
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