ADPGK and GDF9

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
HPRD (two hybrid)

		ADPGK	GDF9
Description		ADP dependent glucokinase	growth differentiation factor 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Extracellular Space Cytoplasm
	Molecular Function	ADP-specific Glucokinase Activity Metal Ion Binding	Cytokine Activity Growth Factor Activity Type I Activin Receptor Binding
	Biological Process	Carbohydrate Metabolic Process Glucose Metabolic Process Glycolytic Process Through Glucose-6-phosphate	Oocyte Growth Transforming Growth Factor Beta Receptor Signaling Pathway Female Gamete Generation Positive Regulation Of Cell Population Proliferation Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Cell Growth BMP Signaling Pathway SMAD Protein Signal Transduction Regulation Of Progesterone Secretion
Pathways		Glycolysis
Drugs
Diseases
GWAS		Adult body size ( 32376654) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Hand grip strength ( 29691431) Triglyceride levels ( 28334899) Urate levels ( 23263486) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Asthma ( 31619474)
Interacting Genes		5 interacting genes: GDF9 OGT TADA3 TCAP UBQLN4	46 interacting genes: ACVR2A ADPGK ANXA7 APLP1 BMP15 BMPR1A BMPR1B BMPR2 BTBD2 CDKN1A CDKN2C CRELD1 DLEU1 DNM2 FOXG1 FXYD6 GADD45G HSPA9 ILF3 KDM1A KIF22 LSM3 MOB4 MPHOSPH6 MYCBP NDUFB9 ORAI2 PABPC4 PAFAH1B3 PCDHA4 PCYT2 PMF1 PRKRA PSMD11 RAB27A RSRC1 S100A8 SAT1 SERPINB9 SMN1 SNRPG STRN4 TDGF1 TK1 TRIB3 WASHC3
Entrez ID		83440	2661
HPRD ID		12429	03560
Ensembl ID		ENSG00000159322	ENSG00000164404
Uniprot IDs		Q9BRR6	B4DXG3 O60383
PDB IDs
Enriched GO Terms of Interacting Partners?
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